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因酮咯酸氨丁三醇导致的弥漫性肺泡出血。

Diffuse alveolar hemorrhage due to ketorolac tromethamine.

机构信息

Division of Pulmonary and Critical Care Medicine, Montefiore Hospital, Albert Einstein College of Medicine, Yeshiva University, New York, N.Y., USA.

出版信息

Pharmacology. 2013;92(1-2):11-3. doi: 10.1159/000351844. Epub 2013 Jul 18.

Abstract

Drug-induced lung disease (DILD) is a common but frequently missed diagnosis. Therefore, a high index of clinical suspicion and familiarity with the clinical syndromes associated with DILD are important in making the diagnosis. Nonsteroidal anti-inflammatory drugs (NSAIDs) are one of the mostly commonly used classes of medications. NSAIDs are safe when used at prescribed doses. Side effects from use of NSAIDs are not uncommon and can affect almost every organ system in the body. NSAIDs are notorious for causing pulmonary toxicity, the common ones being bronchospasm and hypersensitivity reactions. Diffuse alveolar hemorrhage (DAH) secondary to NSAIDs is uncommon. Here, we report a case of DAH secondary to the use of ketorolac tromethamine.

摘要

药物性肺病(DILD)是一种常见但常被漏诊的疾病。因此,高度的临床怀疑指数和熟悉与 DILD 相关的临床综合征对于做出诊断非常重要。非甾体抗炎药(NSAIDs)是最常用的药物类别之一。在规定剂量下使用 NSAIDs 是安全的。使用 NSAIDs 产生的副作用并不少见,几乎可以影响身体的每个器官系统。NSAIDs 以引起肺毒性而臭名昭著,常见的是支气管痉挛和过敏反应。继发于 NSAIDs 的弥漫性肺泡出血(DAH)并不常见。在这里,我们报告了一例继发于酮咯酸氨丁三醇使用的 DAH 病例。

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