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口服苯丙胺后发生弥漫性肺泡出血的罕见病例。

A rare case of diffuse alveolar hemorrhage following oral amphetamine intake.

作者信息

Peters N F, Gosselin R, Verstraete K L

出版信息

JBR-BTR. 2014 Jan-Feb;97(1):42-3. doi: 10.5334/jbr-btr.367.

Abstract

Diffuse alveolar hemorrhage (DAH) is a clinical syndrome, which refers to injury to the capillaries, arterioles and venules, leading to red blood cell accumulation in the distal air spaces. It is defined by the clinical triad of hemoptysis, anemia and progressive hypoxemia. Chest radiographs reveal non-specific patchy or diffuse bilateral pulmonary consolidation. Multiple conditions are associated with DAH, of which Wegener's granulomatosis is the most frequent, and underlying disease determines the prognosis and treatment. This case describes DAH as a result of oral amphetamine abuse in a young patient of which the diagnosis was established by laboratory, clinical and radiologic findings. The patient experienced a rapid recovery without significant sequelae.

摘要

弥漫性肺泡出血(DAH)是一种临床综合征,指毛细血管、小动脉和小静脉受损,导致红细胞在远端气腔中积聚。它由咯血、贫血和进行性低氧血症这一临床三联征定义。胸部X线片显示非特异性斑片状或双侧弥漫性肺部实变。多种疾病与DAH相关,其中韦格纳肉芽肿最为常见,基础疾病决定预后和治疗。本病例描述了一名年轻患者因滥用口服苯丙胺导致的DAH,通过实验室、临床和影像学检查结果确诊。该患者迅速康复,无明显后遗症。

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