J wave is associated with increased risk of sudden cardiac arrest in patients with hypertrophic cardiomyopathy.
作者信息
Li Yanbing, Mao Jun, Yan Qian, Qi Shuyuan, Liu Xiaoyan, Tan Chen, Zhang Ying, Shi Liang, Tian Ying, Wu Yongquan, Zeng Yujie, Wang Jiyun, Chu Jianmin, Ma Changsheng, Liu Xingpeng, Yang Xinchun
机构信息
Heart Centre, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
出版信息
J Int Med Res. 2013 Aug;41(4):1281-90. doi: 10.1177/0300060513487646. Epub 2013 Jul 18.
AIMS
A retrospective, case-control study to investigate the J wave, a J-point elevation on resting 12-lead electrocardiograms, as a risk factor for sudden cardiac arrest (SCA) in patients diagnosed with hypertrophic cardiomyopathy (HCM).
METHODS
Patients with HCM and age- and sex-matched healthy control subjects were recruited, and 12-lead electrocardiograms were performed. The prevalence and related characteristics of J waves were assessed. Patients were followed-up for a mean of 47.9 months.
RESULTS
Patients with HCM (n = 345) had significantly higher prevalence of J waves than healthy controls (n = 690; 11.6% and 7.1%, respectively). During follow-up, 14 patients with HCM experienced SCA (SCA subgroup). The prevalence of J waves was significantly higher in the SCA subgroup than in the non-SCA subgroup (42.9% and 10.3%, respectively). There were no significant differences between the SCA and non-SCA subgroups in J wave morphology.
CONCLUSION
The J wave may be a risk factor for SCA in patients with HCM.
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