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基于超声的自动卵泡计数测量可准确预测体外受精/胞浆内单精子注射周期中成熟卵母细胞的产量。

Follicle measurements using sonography-based automated volume count accurately predict the yield of mature oocytes in in vitro fertilization/intracytoplasmic sperm injection cycles.

机构信息

Centre for Reproductive Medicine, University Hospital Ghent, Belgium.

出版信息

Gynecol Obstet Invest. 2013;76(2):107-12. doi: 10.1159/000353432. Epub 2013 Jul 17.

Abstract

AIMS

We define criteria to predict the number of mature oocytes using automated three-dimensional (3D) ultrasound follicle measurements.

METHODS

Fifty in vitro fertilization/intracytoplasmic sperm injection patients underwent automated 3D echographic monitoring by a single researcher following the stimulation procedure. Classic criteria for triggering oocyte maturation as defined in the literature were utilized. 3D parameters, including the follicular volume and follicle diameter calculated from the volume measurement, were related to the oocyte count, mature oocyte count and the number of observed fertilized oocytes.

RESULTS

We found that when oocyte maturation was induced, 55% of the total follicles with a diameter of at least 10 mm had a volume of at least 1.5 cm³. The number of mature eggs that were retrieved was correlated with the number of follicles observed with a volume of at least 1 cm³ or a calculated follicle diameter of at least 12 mm.

CONCLUSION

Sonography-based automated volume count measurements of follicle volume and reconstructed follicle diameter can be used to reliably predict the number of mature oocytes.

摘要

目的

我们定义了使用自动化三维(3D)超声卵泡测量来预测成熟卵母细胞数量的标准。

方法

50 名体外受精/胞浆内单精子注射患者在刺激过程后由一名研究人员进行自动化 3D 超声监测。使用文献中定义的经典卵母细胞成熟触发标准。3D 参数,包括从体积测量中计算出的卵泡体积和卵泡直径,与卵母细胞计数、成熟卵母细胞计数和观察到的受精卵母细胞数量相关。

结果

我们发现,当诱导卵母细胞成熟时,至少 10mm 直径的总卵泡中有 55%的卵泡体积至少为 1.5cm³。可回收的成熟卵子数量与观察到的至少 1cm³体积或至少 12mm 计算出的卵泡直径的卵泡数量相关。

结论

基于超声的卵泡体积自动容积计数测量和重建卵泡直径可用于可靠地预测成熟卵母细胞的数量。

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