利用高能电子探针追踪单颗粒纳米粒子的三维皮米级运动。

JST/CREST SASAKI-team, Japan Science and Technology Agency, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa City, Chiba, Japan.

Sci Rep. 2013;3:2201. doi: 10.1038/srep02201.

We observed the high-speed anisotropic motion of an individual gold nanoparticle in 3D at the picometer scale using a high-energy electron probe. Diffracted electron tracking (DET) using the electron back-scattered diffraction (EBSD) patterns of labeled nanoparticles under wet-SEM allowed us to super-accurately measure the time-resolved 3D motion of individual nanoparticles in aqueous conditions. The highly precise DET data corresponded to the 3D anisotropic log-normal Gaussian distributions over time at the millisecond scale.

我们使用高能电子探针在皮米尺度上观察到了单个金纳米粒子在 3D 中的高速各向异性运动。在湿扫描电子显微镜下，使用标记纳米粒子的背散射电子衍射（EBSD）花样进行的衍射电子跟踪（DET）使我们能够超精确地测量在水相条件下单个纳米粒子的时间分辨 3D 运动。高度精确的 DET 数据在毫秒尺度上对应于各向异性对数正态高斯分布随时间的变化。