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德国职业性手部接触性皮炎的疾病经济负担。

Cost of illness from occupational hand eczema in Germany.

机构信息

Department of Clinical Social Medicine, Occupational and Environmental Dermatology, University Hospital Heidelberg, 69115 Heidelberg, Germany.

出版信息

Contact Dermatitis. 2013 Aug;69(2):99-106. doi: 10.1111/cod.12038.

Abstract

BACKGROUND

There is little knowledge about the costs of occupational hand eczema.

OBJECTIVES

To estimate the societal costs of patients with occupational hand eczema in Germany.

METHODS

Resource use during the past year, disease severity and quality of life [Dermatology Life Quality Index (DLQI)] were gathered for patients with occupational hand eczema before they entered a special rehabilitation programme. Costs were calculated from the societal perspective. The analysis focused on all patients and the severity groups no signs/mild (group A) and moderate to severe (group B).

RESULTS

One hundred and fifty-one patients were analysed, with a mean age of 44.9years and a mean DLQI score of 10.9; 64.9% were male. Sickness absence was recorded for 62.9% of all patients (76.4days on average in the last 12~months). Annual societal costs were €8799 per patient. Indirect costs represented 70% of total costs. Quality of life (DLQI) was statistically different across both severity groups (group A, 7.9; group B, 12.9), but direct treatment costs were not (€2705 versus €2610, respectively). There was a trend towards higher indirect costs in patients in severity group B (group A, €5120; group B, €6796).

CONCLUSION

The annual societal costs of patients with occupational hand eczema in this study are high, and similar to those for severe psoriasis and atopic dermatitis.

摘要

背景

职业性手部湿疹的费用知之甚少。

目的

评估德国职业性手部湿疹患者的社会成本。

方法

在进入特殊康复计划之前,收集了过去一年中患有职业性手部湿疹的患者的资源利用情况、疾病严重程度和生活质量[皮肤病生活质量指数(DLQI)]。从社会角度计算了成本。分析集中在所有患者和严重程度组无迹象/轻度(A 组)和中度至重度(B 组)。

结果

共分析了 151 例患者,平均年龄为 44.9岁,平均 DLQI 评分为 10.9;64.9%为男性。所有患者中有 62.9%(过去 12个月平均缺勤 76.4~天)记录了病假。每位患者的年社会成本为 8799 欧元。间接成本占总成本的 70%。生活质量(DLQI)在两个严重程度组之间存在统计学差异(A 组,7.9;B 组,12.9),但直接治疗成本没有差异(分别为 2705 欧元和 2610 欧元)。B 组严重程度患者的间接成本呈上升趋势(A 组,5120 欧元;B 组,6796 欧元)。

结论

本研究中职业性手部湿疹患者的年社会成本较高,与严重银屑病和特应性皮炎的成本相当。

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