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2010 年法国监狱囚犯中人类免疫缺陷病毒和丙型肝炎病毒的流行情况:公共卫生政策面临的挑战。

Prevalence of human immunodeficiency virus and hepatitis C virus among French prison inmates in 2010: a challenge for public health policy.

机构信息

Institut de Veille Sanitaire, Saint-Maurice, France.

出版信息

Euro Surveill. 2013 Jul 11;18(28):20524. doi: 10.2807/1560-7917.es2013.18.28.20524.

DOI:10.2807/1560-7917.es2013.18.28.20524
PMID:23870097
Abstract

We evaluated prevalence of human immunodeficiency virus (HIV) and hepatitis C virus (HCV) among prison inmates in France in 2010, in a cross-sectional single-day study based on a two-stage design. Sampling favoured larger establishments and included all types of prisons. Establishments were stratified by geographical region. Estimates were adjusted by post-stratification of the total population of inmates in France. From 60,975 inmates in all 188 prisons on the sampling day, 2,154 were selected from 27 prisons, and 1,876 questionnaires completed. HIV prevalence was estimated at 2.0% (95% confidence interval (CI): 0.9–4.2), 2.6% (95% CI: 0.7–8.8) in women and 2.0% (95% CI: 0.9–4.3) in men; 75% of inmates were receiving treatment for HIV. HCV prevalence was estimated at 4.8% (95% CI: 3.5–6.5) and was higher for women (11.8%; 95% CI: 8.5–16.1) than men (4.5%; 95% CI: 3.3–6.3). Almost half of HCV-infected inmates had chronic hepatitis C and 44% were receiving or had received treatment. HIV and HCV prevalence was six times higher than in the general population, and 2.5% of inmates had viraemic hepatitis C. The moment of incarceration provides an ideal opportunity for testing and treating, limiting spread of HCV and improving patients' prognosis.

摘要

我们评估了 2010 年法国监狱囚犯中人类免疫缺陷病毒(HIV)和丙型肝炎病毒(HCV)的流行情况,这是一项基于两阶段设计的横断面单日研究。抽样偏向于较大的机构,并包括各种类型的监狱。机构按地理位置分层。估计数通过对法国囚犯总数的事后分层进行调整。在所有 188 所监狱的抽样日,从 60975 名囚犯中,从 27 所监狱中选择了 2154 名囚犯,并完成了 1876 份问卷。HIV 感染率估计为 2.0%(95%置信区间(CI):0.9-4.2),女性为 2.6%(95% CI:0.7-8.8),男性为 2.0%(95% CI:0.9-4.3);75%的囚犯正在接受 HIV 治疗。HCV 感染率估计为 4.8%(95% CI:3.5-6.5),女性(11.8%;95% CI:8.5-16.1)高于男性(4.5%;95% CI:3.3-6.3)。几乎一半的 HCV 感染囚犯患有慢性丙型肝炎,44%正在接受或已经接受治疗。HIV 和 HCV 的感染率是普通人群的六倍,2.5%的囚犯患有病毒性丙型肝炎。入狱的时机为检测和治疗提供了理想的机会,限制了 HCV 的传播并改善了患者的预后。

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