Department of Psychology, University of Liège, Liège, Belgium.
Psychiatry Res. 2013 Dec 15;210(2):465-71. doi: 10.1016/j.psychres.2013.06.032. Epub 2013 Jul 16.
Persons diagnosed with bipolar disorder often suffer from cognitive impairments. However, little is known concerning how these cognitive deficits impact their real world functioning. We developed a computerized real-life activity task, where participants are required to shop for a list of grocery store items. Twenty one individuals diagnosed with bipolar disorder and 21 matched healthy controls were administered the computerized shopping task. Moreover, the patient group was assessed with a battery of cognitive tests and clinical scales. Performance on the shopping task significantly differentiated patients and healthy controls for two variables: Total time to complete the shopping task and Mean time spent to consult the shopping list. Moreover, in the patient group, performance on these variables from the shopping task correlated significantly with cognitive functioning (i.e. processing speed, verbal episodic memory, planning, cognitive flexibility, and inhibition) and with clinical variables including duration of illness and real world functioning. Finally, variables from the shopping task were found to significantly explain 41% of real world functioning of patients diagnosed with bipolar disorder. These findings suggest that the shopping task provides a good indication of real world functioning and cognitive functioning of persons diagnosed with bipolar disorder.
被诊断患有双相情感障碍的人常常患有认知障碍。然而,对于这些认知缺陷如何影响他们的现实生活功能,人们知之甚少。我们开发了一种计算机化的现实生活活动任务,要求参与者购买一系列杂货店物品。21 名被诊断患有双相情感障碍的患者和 21 名匹配的健康对照组接受了计算机化购物任务的测试。此外,患者组还接受了一系列认知测试和临床量表的评估。购物任务的表现显著区分了患者和健康对照组的两个变量:完成购物任务的总时间和查看购物清单的平均时间。此外,在患者组中,购物任务的表现与认知功能(即处理速度、词语情景记忆、计划、认知灵活性和抑制)以及包括疾病持续时间和现实生活功能在内的临床变量显著相关。最后,购物任务的变量可以显著解释被诊断患有双相情感障碍的患者 41%的现实生活功能。这些发现表明,购物任务可以很好地反映被诊断患有双相情感障碍的人的现实生活功能和认知功能。