Department of Chemistry and Nanoscience and Nanotechnology, National Sun Yat-sen University, Kaohsiung City 80424, Taiwan.
Food Chem. 2013 Dec 1;141(3):2117-21. doi: 10.1016/j.foodchem.2013.04.115. Epub 2013 May 9.
The eggshell membrane (ESM) is a naturally occurring biological polymer, which can be extracted from eggshells, and has been used for adsorption of dyes or heavy metals, as a semipermeable membrane to control particle transport, and as a natural biocompatible material for tissue replacement. In this study, we used hydrogen peroxide to control the pore size and fibre crossing density of the ESM. Structural and chemical properties were investigated using AFM, optical microscopy, contact angle, and FTIR. We show that the structure and permeability of the ESM can be controlled by timed exposure to H2O2 and we demonstrate this effect using red blood cells. This process provides a simple method for preparing biocompatible membranes, with controlled selectivity for biofiltration applications.
蛋壳膜（ESM）是一种天然存在的生物聚合物，可从蛋壳中提取，已被用于吸附染料或重金属、作为半透膜控制颗粒传输，以及作为用于组织替代的天然生物相容性材料。在这项研究中，我们使用过氧化氢来控制 ESM 的孔径和纤维交叉密度。使用原子力显微镜、光学显微镜、接触角和傅里叶变换红外光谱研究了结构和化学性质。我们表明，ESM 的结构和渗透性可以通过定时暴露于 H2O2 来控制，我们使用红细胞证明了这种效果。该过程提供了一种用于制备生物相容性膜的简单方法，对生物过滤应用具有可控的选择性。
