钯催化水中碘代芳烃与酚的对位选择性芳基化反应。

Palladium-catalyzed para-selective arylation of phenols with aryl iodides in water.

机构信息

Institute of Homogeneous Catalysis, College of Chemistry, Sichuan University, Chengdu 610064, PR China.

出版信息

Chem Commun (Camb). 2013 Sep 7;49(69):7653-5. doi: 10.1039/c3cc44345k. Epub 2013 Jul 22.

Abstract

Highly para-selective palladium-catalyzed direct arylation of phenols with aryl iodides was demonstrated by taking advantage of the formal inverse direct arylation strategy. A series of 4-aryl phenols were synthesised by employing water as a "green" solvent under mild reaction conditions.

摘要

利用形式上的反直接芳基化策略，实现了高度对映选择性的钯催化酚与芳基碘化物的直接芳基化。在温和的反应条件下，以水为“绿色”溶剂，合成了一系列 4-芳基苯酚。