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1
Targeting H3K4 trimethylation in Huntington disease.
Proc Natl Acad Sci U S A. 2013 Aug 6;110(32):E3027-36. doi: 10.1073/pnas.1311323110. Epub 2013 Jul 19.
2
The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases.
Cell. 2007 Mar 23;128(6):1077-88. doi: 10.1016/j.cell.2007.02.017. Epub 2007 Feb 22.
5
The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation.
Nature. 2007 May 31;447(7144):601-5. doi: 10.1038/nature05823. Epub 2007 Apr 29.
7
Reduced expression of the TrkB receptor in Huntington's disease mouse models and in human brain.
Eur J Neurosci. 2006 Feb;23(3):649-58. doi: 10.1111/j.1460-9568.2006.04590.x.
8
Balancing of histone H3K4 methylation states by the Kdm5c/SMCX histone demethylase modulates promoter and enhancer function.
Cell Rep. 2013 Apr 25;3(4):1071-9. doi: 10.1016/j.celrep.2013.02.030. Epub 2013 Mar 28.
9
Altered histone monoubiquitylation mediated by mutant huntingtin induces transcriptional dysregulation.
J Neurosci. 2008 Apr 9;28(15):3947-57. doi: 10.1523/JNEUROSCI.5667-07.2008.
10
Modulation of nucleosome dynamics in Huntington's disease.
Hum Mol Genet. 2007 May 15;16(10):1164-75. doi: 10.1093/hmg/ddm064. Epub 2007 Apr 2.

引用本文的文献

1
Inhibition of class IIa HDACs reduces mutant HTT aggregation by affecting RNA stability.
Front Mol Neurosci. 2025 Jun 18;18:1579194. doi: 10.3389/fnmol.2025.1579194. eCollection 2025.
3
Accelerated epigenetic aging in Huntington's disease involves polycomb repressive complex 1.
Nat Commun. 2025 Feb 11;16(1):1550. doi: 10.1038/s41467-025-56722-z.
4
G9a an Epigenetic Therapeutic Strategy for Neurodegenerative Conditions: From Target Discovery to Clinical Trials.
Med Res Rev. 2025 May;45(3):985-1015. doi: 10.1002/med.22096. Epub 2025 Jan 6.
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The Two Faces of HDAC3: Neuroinflammation in Disease and Neuroprotection in Recovery.
Epigenomics. 2024 Nov-Nov;16(21-22):1373-1388. doi: 10.1080/17501911.2024.2419357. Epub 2024 Nov 8.
6
Exploring the Frontier: Antisense Long Non-Coding RNAs as Key Regulators in Alzheimer's Disease.
Aging Dis. 2024 Aug 19;16(4):1793-1812. doi: 10.14336/AD.2024.0762.
7
Dysregulation of choline metabolism and therapeutic potential of citicoline in Huntington's disease.
Aging Cell. 2024 Nov;23(11):e14302. doi: 10.1111/acel.14302. Epub 2024 Aug 14.
8
Epigenetic modulators provide a path to understanding disease and therapeutic opportunity.
Genes Dev. 2024 Jul 19;38(11-12):473-503. doi: 10.1101/gad.351444.123.
9
Neuroinflammation and the role of epigenetic-based therapies for Huntington's disease management: the new paradigm.
Inflammopharmacology. 2024 Jun;32(3):1791-1804. doi: 10.1007/s10787-024-01477-0. Epub 2024 Apr 23.
10
HD and SCA1: Tales from two 30-year journeys since gene discovery.
Neuron. 2023 Nov 15;111(22):3517-3530. doi: 10.1016/j.neuron.2023.09.036. Epub 2023 Oct 19.

本文引用的文献

1
Extensive changes in DNA methylation are associated with expression of mutant huntingtin.
Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2354-9. doi: 10.1073/pnas.1221292110. Epub 2013 Jan 22.
4
Epigenetic signatures of autism: trimethylated H3K4 landscapes in prefrontal neurons.
Arch Gen Psychiatry. 2012 Mar;69(3):314-24. doi: 10.1001/archgenpsychiatry.2011.151. Epub 2011 Nov 7.
5
Identifying polyglutamine protein species in situ that best predict neurodegeneration.
Nat Chem Biol. 2011 Oct 30;7(12):925-34. doi: 10.1038/nchembio.694.
6
What have we learned from gene expression profiles in Huntington's disease?
Neurobiol Dis. 2012 Jan;45(1):83-98. doi: 10.1016/j.nbd.2011.07.001. Epub 2011 Jul 12.
8
ChIP-seq analysis reveals distinct H3K27me3 profiles that correlate with transcriptional activity.
Nucleic Acids Res. 2011 Sep 1;39(17):7415-27. doi: 10.1093/nar/gkr416. Epub 2011 Jun 7.
9
Cell type-specific DNA methylation at intragenic CpG islands in the immune system.
Genome Res. 2011 Jul;21(7):1074-86. doi: 10.1101/gr.118703.110. Epub 2011 May 31.
10
Aligning short sequencing reads with Bowtie.
Curr Protoc Bioinformatics. 2010 Dec;Chapter 11:Unit 11.7. doi: 10.1002/0471250953.bi1107s32.

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