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阿片类药物维持治疗患者的急性疼痛管理:急诊科医生在做什么?

Acute pain management for patients under opioid maintenance treatment: what physicians do in emergency departments?

机构信息

aPharmacoépidémiology, UMR1027, INSERM, Toulouse University III bDepartment of Clinical Pharmacology, Pharmacodependence-Evaluation and Information Center (CEIP-A) cEmergency Department, University Hospital of Toulouse, Toulouse, France.

出版信息

Eur J Emerg Med. 2014 Feb;21(1):73-6. doi: 10.1097/MEJ.0b013e328363c9e0.

Abstract

The aim of this study was to analyze the current practices on acute pain management of patients under opioid maintenance treatment (OMT), that is, buprenorphine or methadone. A total of 706 physicians were solicited through a national network to answer a survey about pain perception and analgesic strategies. Among the prescribers, 323 (46%) answered the survey: 131 (40%) physicians estimated that patients under OMT when exposed to an acute painful event feel more pain than other patients and 170 (53%) estimated that the patients felt the same amount of pain. Use of WHO step 1 analgesics was reported by 283 (88%) prescribers [264 (82%) prescribers reported use of paracetamol and 178 (55%) reported use of NSAIDs]. Among the second-line analgesic drugs, the WHO step 3 analgesics (mainly morphine) were the most commonly reported [221 physicians (68%)]. Overall, the results demonstrate the misconceptions of physicians on the pain tolerance of patients under OMT. Clinical studies and evidence-based guidelines are necessary to improve the therapeutic strategies for such patients in an emergency setting.

摘要

本研究旨在分析目前接受阿片类药物维持治疗(OMT)的患者(即丁丙诺啡或美沙酮)的急性疼痛管理现状。通过国家网络向 706 名医生征求意见,以回答有关疼痛感知和镇痛策略的调查。在开处方的医生中,有 323 名(46%)回答了调查:131 名(40%)医生估计接受 OMT 的患者在遇到急性疼痛事件时会感到比其他患者更痛,而 170 名(53%)医生估计患者感到同样程度的疼痛。283 名(88%)医生报告使用了世界卫生组织(WHO)第 1 步镇痛药[264 名(82%)医生报告使用对乙酰氨基酚,178 名(55%)报告使用 NSAIDs]。在二线镇痛药中,WHO 第 3 步镇痛药(主要是吗啡)是最常报告的药物[221 名医生(68%)]。总体而言,这些结果表明医生对 OMT 患者的疼痛耐受力存在误解。临床研究和循证指南对于改善此类患者在紧急情况下的治疗策略是必要的。

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