眼内弓形体虫囊肿在眼周/眼内曲安奈德注射后伴坏死性视网膜炎的患者中。
Intraocular cysts of toxoplasma gondii in patients with necrotizing retinitis following periocular/intraocular triamcinolone injection.
机构信息
Department of Cytology & Gynecological Pathology and.
出版信息
Ocul Immunol Inflamm. 2013 Oct;21(5):396-9. doi: 10.3109/09273948.2013.810276. Epub 2013 Jul 22.
PURPOSE
To report the detection of Toxoplasma gondii cysts in intraocular aspirates of patients with necrotizing retinitis following periocular/intraocular corticosteroid injection.
DESIGN
Case report.
METHODS
Two patients (2 eyes) with widespread necrotizing retinitis in a steroid-exposed eye posed a diagnostic challenge and underwent pars plana vitrectomy (PPV). Intraocular samples (vitreous fluid, retinal tissue, and subretinal aspirate in case 1, and vitreous fluid in case 2) were subjected to cytological examination.
RESULTS
The subretinal aspirate (case 1) revealed encysted bradyzoites of Toxoplasma gondii. Vitreous fluid (case 2) tested positive for anti-toxoplasma antibodies and the smear showed encysted forms of Toxoplasma gondii on cytology. CONCLUSION. Toxoplasma gondii cysts were detected in eyes with necrotizing retinitis that developed secondary to injudicious use of corticosteroids.
目的
报告在眼周/眼内皮质类固醇注射后发生坏死性视网膜炎的患者的眼内吸出物中检测到刚地弓形虫包囊。
设计
病例报告。
方法
2 名（2 只眼）广泛坏死性视网膜炎的皮质类固醇暴露眼患者提出了诊断挑战，并接受了经睫状体平坦部玻璃体切除术（PPV）。对眼内样本（玻璃体液、视网膜组织和 1 例中的视网膜下吸出物，以及 2 例中的玻璃体液）进行细胞学检查。
结果
视网膜下吸出物（病例 1）显示刚地弓形虫包囊缓殖子。玻璃体液（病例 2）对弓形虫抗体检测呈阳性，涂片显示细胞学上存在刚地弓形虫包囊。
结论
在因不合理使用皮质类固醇而发生坏死性视网膜炎的眼中检测到刚地弓形虫包囊。
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