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经内镜超声细针活检术术前诊断胰腺实性假乳头状瘤:回顾性病例系列研究。

Preoperative diagnosis of a solid pseudopapillary tumour of the pancreas by Endoscopic Ultrasound Fine Needle Biopsy: A retrospective case series.

机构信息

Unit of Gastroenterology, AUSL Bologna Bellaria-Maggiore Hospital, Bologna, Italy.

出版信息

Dig Liver Dis. 2013 Nov;45(11):957-60. doi: 10.1016/j.dld.2013.06.005. Epub 2013 Jul 19.

Abstract

BACKGROUND

A solid pseudopapillary tumour of the pancreas (SPTP) is a rare neoplasm.

AIM

We herein present five cases of SPTP diagnosed using endoscopic ultrasound (EUS) guided fine-needle biopsy (FNB) using a needle with side fenestration (ProCore-needle).

METHODS

From January 2011 to June 2012 in five patients with SPTP tissue acquisition was carried out with a 19-gauge (4 patients) or a 22-gauge (one patient) needle.

RESULTS

The mean age of the patients was 30.8 years, the mean lesion size was 49mm and the most common location was the tail of the pancreas (3 cases). When the samples were evaluated macroscopically, small core fragments were observed in all cases. A preoperative diagnosis of SPTP was made in all patients on the basis of the histocytological and characteristic immunophenotypic patterns and was confirmed at final surgical histology.

CONCLUSIONS

In our experience, EUS-FNB is an effective and secure method for a preoperative diagnosis of SPTP.

摘要

背景

胰腺实性假乳头状瘤(SPTP)是一种罕见的肿瘤。

目的

我们在此介绍 5 例经内镜超声(EUS)引导下使用带有侧孔的细针(ProCore 针)进行的 FNB 诊断为 SPTP 的病例。

方法

2011 年 1 月至 2012 年 6 月,对 5 例 SPTP 患者进行了 19 号(4 例)或 22 号(1 例)针的穿刺以获取组织。

结果

患者的平均年龄为 30.8 岁,平均病变大小为 49mm,最常见的部位是胰腺尾部(3 例)。所有病例的标本均观察到小的核心碎片。所有患者均根据组织细胞学和特征性免疫表型模式在术前诊断为 SPTP,并在最终的外科组织学中得到证实。

结论

根据我们的经验,EUS-FNB 是一种有效且安全的方法,可用于 SPTP 的术前诊断。

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