Lanke Gandhi, Ali Faisal S, Lee Jeffrey H
Department of Gastroenterology, Hepatology and Nutrition, University of Texas MD Anderson Cancer Center, Houston, TX 77030, United States.
World J Gastrointest Endosc. 2018 Sep 16;10(9):145-155. doi: 10.4253/wjge.v10.i9.145.
Solid pseudopapillary neoplasm (SPN) is a rare tumor with malignant potential which is generally located in the tail of pancreas. The prevalence of SPN has increased with widespread use of cross sectional imaging. SPN is often misdiagnosed due to nonspecific clinical presentation and accurate diagnosis is essential for optimal management. Endoscopic ultrasound-FNA with immunohistochemistry can help in preoperative diagnosis. Surgery is the treatment of choice and a successful R0 resection is curative. Overall, SPN has a good prognosis. This review article focuses on pathogenesis, diagnosis and management of SPN.
实性假乳头状肿瘤（SPN）是一种具有恶性潜能的罕见肿瘤，通常位于胰腺尾部。随着横断面成像技术的广泛应用，SPN的发病率有所上升。由于临床表现不具特异性，SPN常被误诊，而准确诊断对于优化治疗至关重要。内镜超声引导下细针穿刺活检联合免疫组织化学有助于术前诊断。手术是首选治疗方法，成功的R0切除可治愈疾病。总体而言，SPN预后良好。这篇综述文章重点关注SPN的发病机制、诊断和治疗。
