Huo Yusen, Duan Hongjie, Liu Lingying, Hu Quan, Chai Jiake
Department of Burn & Plastic Surgery, the First Affiliated Hospital of Chinese PLA General Hospital, Beijing, 100037, PR China.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2013 May;27(5):571-4.
To review the research progress of mesenchymal stem cells (MSCs) in burn wound repair.
The recent literature about MSCs involved in burn wound repair and mechanism was extensively reviewed and analyzed.
MSCs have the capacity of self-renew, rapid proliferation, differentiation and paracrine, and promote burn wound repair through differentiating into a series of skin wound cells and regulating wound microenvironment.
MSCs have great potentials in the burn field. However, the cell survival and outcome are also facing challenges from poor microenvironment of the burn wound.
综述间充质干细胞（MSCs）在烧伤创面修复中的研究进展。
广泛查阅并分析近期有关MSCs参与烧伤创面修复及其机制的文献。
MSCs具有自我更新、快速增殖、分化及旁分泌能力，通过分化为一系列皮肤创面细胞及调节创面微环境促进烧伤创面修复。
MSCs在烧伤领域具有巨大潜力。然而，细胞存活及疗效也面临着烧伤创面恶劣微环境的挑战。
