Zupan Andrej, Vrabec Katarina, Glavač Damjan
Department of Molecular Genetics, Institute of Pathology, Faculty of Medicine, University of Ljubljana , 1000 Ljubljana , Slovenia.
Ann Hum Biol. 2013 Nov-Dec;40(6):515-26. doi: 10.3109/03014460.2013.813584. Epub 2013 Jul 23.
The Slovenian territory is geographically positioned between the Alps, the Adriatic Sea, the Pannonian basin and the Dinaric Mountains and, as such, has served as a passageway for different populations over different periods of time. Turbulent historic events and the diverse geography of the region have produced a diverse contemporary population whose genetic analysis could provide insight into past demographic events.
The aim of this study was to analyse Y-chromosome biallelic and STR markers in a Slovenian population from five different regions.
A total of 42 Y-chromosomal biallelic markers and 17 Y-STRs were genotyped in 399 individuals from five different Slovenian regions.
The analysis of Y-chromosome markers revealed 29 different haplogroups in the Slovenian population, with the most common being R1a1a, R1b, I2a1 and I1. Analysis of the genetic affiliations between different populations revealed strong affiliations of the Slovenian gene pool with West Slavic populations.
Analysis of Y-chromosomal markers in five Slovenian regions revealed a diverse genetic landscape. Slovenian population display close genetic affiliations with West Slavic populations. The homogenous genetic strata of the West Slavic populations and the Slovenian population suggest the existence of a common ancestral Slavic population in central European region.
斯洛文尼亚领土在地理位置上介于阿尔卑斯山脉、亚得里亚海、潘诺尼亚盆地和迪纳拉山脉之间，因此在不同时期一直是不同人群的通道。动荡的历史事件和该地区多样的地理环境造就了一个多样化的当代人口群体，对其进行基因分析可以洞察过去的人口事件。
本研究的目的是分析来自斯洛文尼亚五个不同地区的人群的Y染色体双等位基因和STR标记。
对来自斯洛文尼亚五个不同地区的399名个体的42个Y染色体双等位基因标记和17个Y-STR进行基因分型。
Y染色体标记分析在斯洛文尼亚人群中发现了29种不同的单倍群，最常见的是R1a1a、R1b、I2a1和I1。对不同人群之间遗传关系的分析表明，斯洛文尼亚基因库与西斯拉夫人群有很强的亲缘关系。
对斯洛文尼亚五个地区的Y染色体标记分析揭示了一个多样化的遗传格局。斯洛文尼亚人群与西斯拉夫人群显示出密切的遗传关系。西斯拉夫人群和斯洛文尼亚人群的同质遗传层次表明中欧地区存在一个共同的斯拉夫祖先群体。
