Bartels H, Spring P
Chemotherapy. 1975;21(1):1-10. doi: 10.1159/000221838.
A method for the determination of isonicotinic acid hydrazide is given. The hydrazide is complexed with cupric ions and condensated with an aromatic aldehyde substituted in ortho-position with a hydroxyl group. The method is adapted to the AutoAnalyzer equipment of first and second generation. Pilot measurements on the pharmacokinetic behaviour of isonicotinic acid hydrazide are presented.
给出了一种测定异烟肼的方法。该酰肼与铜离子络合，并与在邻位被羟基取代的芳香醛缩合。该方法适用于第一代和第二代自动分析仪设备。介绍了异烟肼药代动力学行为的初步测量。
