Wang Qi, Qin Jing, Gai Lu-yue, Wang Zhi-guo, Guan Zhi-wei, Sun Zhi-jun, Dong Wei, Yang Li, Chen Yun-dai
Department of Cardiology, Chinese People's Liberation Army General Hospital, Beijing 100853, China.
Zhonghua Xin Xue Guan Bing Za Zhi. 2013 Mar;41(3):199-204.
To assess the feasibility and accuracy of CT first-pass myocardial perfusion imaging (CT first-pass MPI) at rest for diagnosis of myocardial ischemia. Results of adenosine-induced myocardial perfusion scintigraphy (MPS) were used as gold standard.
Twenty-two patients with suspected or diagnosed coronary artery disease (CAD) were included and CT coronary angiography (CTCA) and MPS were performed within 2 weeks. CT first-pass MPI detected myocardial ischemia results through analyzing the raw date of CTCA were compared with MPS results.
The sensibility, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy of CT first-pass MPI at rest for detecting myocardial ischemia were 92% (12/13), 78% (7/9), 86% (12/14), 88% (7/8) and 86% (19/22), respectively.
CT first-pass MPI at rest could detect myocardial ischemia with an accuracy similar to that of MPS.
评估静息状态下CT首过心肌灌注成像（CT首过心肌灌注显像，CT first-pass MPI）诊断心肌缺血的可行性和准确性。腺苷负荷心肌灌注显像（MPS）结果作为金标准。
纳入22例疑似或确诊冠心病（CAD）患者，在2周内进行CT冠状动脉造影（CTCA）和MPS检查。CT首过心肌灌注显像通过分析CTCA原始数据检测心肌缺血结果，并与MPS结果进行比较。
静息状态下CT首过心肌灌注显像检测心肌缺血的敏感性、特异性、阳性预测值（PPV）、阴性预测值（NPV）和准确性分别为92%（12/13）、78%（7/9）、86%（12/14）、88%（7/8）和86%（19/22）。
静息状态下CT首过心肌灌注显像检测心肌缺血的准确性与MPS相似。
