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一种实用且客观的瘢痕颜色评估方法。

A practical and objective approach to scar colour assessment.

机构信息

Queen Victoria Hospital, Holtye Road, East Grinstead, UK.

出版信息

J Plast Reconstr Aesthet Surg. 2013 Oct;66(10):e271-6. doi: 10.1016/j.bjps.2013.06.021. Epub 2013 Jul 21.

Abstract

Scarring is a significant clinical problem following dermal injury. However, scars are not a single describable entity and huge phenotypic variability is evident. Quantitative, reproducible inter-observer scar assessment is essential to monitor wound healing and the effect of scar treatments. Scar colour, reflecting the biological processes occurring within a scar, is integral to any assessment. The objective of this study was to analyse scar colour using the non-invasive Eykona® Wound Measurement System (the System) as compared against the Manchester Scar Scale (MSS). Three dimensional images of 43 surgical scars were acquired post-operatively from 35 patients at 3-6 months and the colour difference between the scar and surrounding skin was calculated (giving ΔLab values). The colourimetric results were then compared against subjective MSS gradings. A significant difference in ΔLab values between MSS gradings of "slight mismatch" and "obvious mismatch" (p<0.025) and between "obvious mismatch" and "gross mismatch" (p<0.05) were noted. The System creates objective, reproducible data, without the need for any specialist expertise and compares favourably with the MSS. Greater scar numbers are required to further clinically validate this device--however, with this potential to calculate scar length, width, volume and other characteristics, it could provide a complete, objective, quantitative record of scarring throughout the wound-healing process.

摘要

瘢痕是皮肤损伤后的一个重要临床问题。然而,瘢痕并不是单一可描述的实体,存在巨大的表型变异性。定量、可重复的观察者间瘢痕评估对于监测伤口愈合和瘢痕治疗效果至关重要。瘢痕颜色反映了瘢痕内发生的生物学过程,是任何评估的重要组成部分。本研究的目的是使用非侵入性的 Eykona®伤口测量系统(该系统)分析瘢痕颜色,并与曼彻斯特瘢痕量表(MSS)进行比较。从 35 名患者的 43 个手术瘢痕中,在术后 3-6 个月获取三维图像,并计算瘢痕与周围皮肤之间的颜色差异(给出ΔLab 值)。然后将色度结果与主观 MSS 分级进行比较。MSS 分级为“轻微不匹配”和“明显不匹配”(p<0.025)以及“明显不匹配”和“严重不匹配”(p<0.05)之间的ΔLab 值存在显著差异。该系统可生成客观、可重复的数据,无需任何专业知识,与 MSS 相比具有优势。需要更多的瘢痕数量来进一步验证该设备的临床应用,但它具有计算瘢痕长度、宽度、体积和其他特征的潜力,因此可以为伤口愈合过程中的瘢痕提供完整、客观、定量的记录。

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