Roahen J O, Marshall F J
Dental Corps, U.S. Navy, Annapolis, MD.
J Endod. 1990 Jan;16(1):28-33. doi: 10.1016/s0099-2399(07)80027-6.
This study was designed to investigate histologically the effects of the periodontal ligament injection on the pulp of teeth with or without subsequent amalgam restorations, and the effects of the injection on the periodontium. Eighty-eight injections were made on 55 teeth in dogs in intervals from 10-min to 30-day prefixation, while 18 teeth were not injected and evaluated as controls. After perfusion fixation, block sections were decalcified, sectioned longitudinally, stained, and evaluated microscopically by three independent examiners. The pulps were graded for degree of inflammation and the periodontal ligaments were examined for signs of tissue disruption. The results of the pulp study were evaluated statistically and showed no apparent effect on the pulp from the injection. Several periodontal ligaments showed evidence of the injection, ranging from tissue disruption shortly postinjection to areas of active external root resorption in 30-day specimens. It was concluded that this technique does not have long-term deleterious effects on the pulp, but can induce localized external root resorption.
本研究旨在通过组织学方法调查牙周膜注射对有或无后续汞合金修复体牙齿牙髓的影响，以及该注射对牙周组织的影响。在犬的55颗牙齿上进行了88次注射，注射时间间隔为10分钟至30天前固定，同时18颗牙齿未注射作为对照进行评估。灌注固定后，将块状切片脱钙、纵向切片、染色，并由三名独立的检查人员进行显微镜评估。对牙髓的炎症程度进行分级，并检查牙周膜有无组织破坏迹象。对牙髓研究结果进行统计学评估，结果显示注射对牙髓无明显影响。一些牙周膜显示出注射的证据，从注射后不久的组织破坏到30天标本中活跃的外吸收区域不等。得出的结论是，该技术对牙髓没有长期有害影响，但可诱发局限性外吸收。
