Department of Otorhinolaryngology-Head and Neck Surgery, Rabin Medical Center, Petah Tikva, Israel,
Eur Arch Otorhinolaryngol. 2014 May;271(5):1215-8. doi: 10.1007/s00405-013-2636-4. Epub 2013 Jul 24.
The value of ultrasound in detecting central compartment lymph node metastasis in patients with well-differentiated thyroid carcinoma (WDTC) is unclear. Prospective patients with WDTC attending a university-affiliated tertiary medical center between July 2010 and June 2011 underwent neck ultrasound for detection of central compartment lymph node metastases prior to surgery. Central lymph node dissection was performed during the initial surgery regardless of ultrasound findings. The sensitivity and specificity of preoperative ultrasound in detecting central lymph node metastases were calculated according to the final histopathological results. Sixty-four patients met the study criteria. Twenty-four had pathologic central compartment lymph nodes according to preoperative ultrasound, 20 of which were confirmed by histological examination. One patient was found to have pathological central lymph nodes by histology which was not detected by US. Sensitivity of preoperative ultrasound was 95%, specificity 90%, and negative and positive predictive values 97 and 83%, respectively. Preoperative ultrasound may serve as an accurate and important tool for deciding the extent of surgery in WDTC.
超声在检测分化型甲状腺癌（WDTC）患者中央区淋巴结转移中的价值尚不清楚。2010 年 7 月至 2011 年 6 月期间，在一所大学附属医院就诊的 WDTC 前瞻性患者在手术前进行颈部超声检查以检测中央区淋巴结转移。无论超声检查结果如何，中央淋巴结清扫术均在初次手术中进行。根据最终的组织病理学结果计算术前超声检测中央淋巴结转移的敏感性和特异性。64 例患者符合研究标准。24 例患者术前超声显示中央区淋巴结有病变，其中 20 例经组织学检查证实。1 例患者的组织学检查发现了超声未检测到的病理性中央淋巴结。术前超声的敏感性为 95%，特异性为 90%，阴性预测值和阳性预测值分别为 97%和 83%。术前超声可能成为 WDTC 手术范围决策的一种准确而重要的工具。
