子痫前期女性极低出生体重儿的中性粒细胞减少和血小板减少
Neutropenia and thrombocytopenia in very low birth weight infants of women with preeclampsia.
作者信息
Claudio Norma A, García Inés, García Lourdes, Valcárcel Marta
机构信息
Department of Pediatrics, Neonatology Section, UPR School of Medicine and University Pediatric Hospital, San Juan, Puerto Rico.
出版信息
Bol Asoc Med P R. 2013;105(2):9-14.
OBJECTIVE
Determine the incidence of neutropenia and thrombocytopenia during the first week of life in very low birth weight (VLBW) infants born to mothers with preeclampsia.
METHODS
Medical records of infants born to mothers with preeclampsia admitted to NICU from 2005-2007 were reviewed.
RESULTS
A total of 93 infants were included with a mean birth weight of 988 g and gestational age of 29 weeks. Neutropenia was present in 49% of the infants and thrombocytopenia in 56%. Infants with neutropenia had lower birth weights (p<0.01) and were born at lower gestational ages (p<0.01). Neutropenia was associated to a higher prevalence of positive blood cultures during the first week of life especially coagulase negative organisms.
CONCLUSIONS
In this group of VLBW infants born to mothers with preeclampsia, neutropenia was common and it was associated to increase risk of bacterial infections during the first week of life.
目的
确定子痫前期母亲所生极低出生体重（VLBW）婴儿出生后第一周内中性粒细胞减少症和血小板减少症的发生率。
方法
回顾了2005年至2007年入住新生儿重症监护病房（NICU）的子痫前期母亲所生婴儿的病历。
结果
共纳入93例婴儿，平均出生体重988克，胎龄29周。49%的婴儿出现中性粒细胞减少症，56%的婴儿出现血小板减少症。中性粒细胞减少症婴儿的出生体重较低（p<0.01），出生时的胎龄也较小（p<0.01）。中性粒细胞减少症与出生后第一周血培养阳性的发生率较高有关，尤其是凝固酶阴性菌。
结论
在这组子痫前期母亲所生的VLBW婴儿中，中性粒细胞减少症很常见，并且与出生后第一周细菌感染风险增加有关。
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