US Army Medical Department Center and School, Department of Emergency Medicine, Brooke Army Medical Center, Fort Sam Houston, Texas 78234-6315, USA.
J Trauma Acute Care Surg. 2013 Aug;75(2 Suppl 2):S164-8. doi: 10.1097/TA.0b013e31829be079.
This study aimed to analyze demographic, epidemiologic, temporal, and outcome data from an integrated trauma registry of patients undergoing initial stabilization and transfer within a mature domestic trauma network; compare data with a companion subset from the Department of Defense Trauma Registry. Texas Trauma Service Area-P is composed of 25 counties, 15 rural Level IV trauma centers (no acute care surgery), and two Level I trauma centers.
This study has a retrospective cohort design. We hypothesize that Injury Severity Scores (ISSs), time intervals, and other clinical indicators would be complimentary to contemporary combat casualties. Inclusion criteria include age 18 years to 80 years, transferred from Level IV to Level I trauma center, or expired en route.
A total of 543 subjects (84%) met the criteria and were analyzed. Averages and confidence intervals were as follows: age of 40 years (38-41 years), males at 81%, ISS of 10 (10-11), intensive care unit stay of 2 days (1-3 days), and hospital stay of 5 days (4-6 days). Mechanisms of injury were as follows: penetrating (15%), blunt weapon (19%), stabs (9%), burns (5%), and gunshots (5%). Eight percent received blood within the first 24 hours. Survival was at 98%. Time intervals (95% confidence interval) were as follows: prehospital at 1:43 (1:29-1:58), Level IV dwell time at 3:17 (3:06-3:28), interfacility transfer at 1:43 (1:36-1:49), and total at 6:39 (6:20-6:58). RemTORN cases were older, spent longer time en route to Level I, and had ISS similar to combat casualties. Rates of blood transfusion in the first 24 hours and survival were similar in order of magnitude.
The RemTORN platform is operational. Demographic, epidemiologic, and temporal characteristics as observed will support clinical investigations of traumatic coagulopathy, shock, and potential interventions before Level I arrival. Results of such investigations will likely be applicable to the contemporary and future battlefield.
本研究旨在分析一个成熟的国内创伤网络中接受初始稳定和转院的创伤患者的人口统计学、流行病学、时间和结局数据;并与来自国防部创伤登记处的一组配对数据进行比较。德克萨斯创伤服务区-P 由 25 个县、15 个农村四级创伤中心(无急性护理手术)和 2 个一级创伤中心组成。
本研究采用回顾性队列设计。我们假设损伤严重程度评分(ISS)、时间间隔和其他临床指标将与当代战斗伤亡人员互补。纳入标准包括年龄 18 岁至 80 岁,从四级创伤中心转至一级创伤中心,或在转院途中死亡。
共有 543 名(84%)符合标准并进行了分析。平均值和置信区间如下:年龄 40 岁(38-41 岁),男性占 81%,ISS 为 10(10-11),重症监护病房住院 2 天(1-3 天),住院 5 天(4-6 天)。受伤机制如下:穿透伤(15%)、钝器伤(19%)、刺伤(9%)、烧伤(5%)和枪伤(5%)。8%的患者在 24 小时内接受输血。存活率为 98%。时间间隔(95%置信区间)如下:院前 1:43(1:29-1:58),四级停留时间 3:17(3:06-3:28),院内转运 1:43(1:36-1:49),总时间 6:39(6:20-6:58)。RemTORN 病例年龄较大,在到达一级创伤中心的途中花费的时间较长,ISS 与战斗伤亡人员相似。前 24 小时输血率和存活率的量级相似。
RemTORN 平台已投入运行。观察到的人口统计学、流行病学和时间特征将支持创伤性凝血病、休克和潜在干预措施的临床研究,以便在到达一级创伤中心之前进行。此类研究的结果可能适用于当代和未来的战场。