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阻塞性睡眠呼吸暂停综合征患者的记忆监测和记忆控制。

Memory monitoring and memory control in patients suffering from obstructive sleep apnoea syndrome.

机构信息

a UMR 5263 CNRS - EPHE - Toulouse II University, "CLLE-LTC" Laboratory , Toulouse , France.

出版信息

Memory. 2014;22(6):710-21. doi: 10.1080/09658211.2013.818156. Epub 2013 Jul 26.

Abstract

Patients with obstructive sleep apnoea syndrome exhibit memory deficit. The present study looked at whether this deficit is related to impaired memory monitoring and/or memory control. Here 25 patients and 26 healthy controls performed a paired-associate learning task. After participants had made a judgement of learning for each pair and performed an initial recall test they were free to restudy any items they wished, for as long or little as they wished, within a 5-minute period. They then performed a second recall test. Monitoring and control processes were assessed on the basis of judgements of learning, item selection, and study-time allocation. In spite of their memory impairment, patients accurately predicted their recall. For the restudy phase patients preferentially selected the judged-easy items, while controls selected the judged-difficult items. However, all the participants allocated more restudy time to the judged-difficult items than to the judged-easy ones. There were no significant correlations between memory performance, metamemory processes, and clinical measures (i.e., subjective sleepiness, subjective sleep quality, anxiety, and depression scores). Results suggested that both memory monitoring and memory control were preserved in our sample of patients with obstructive sleep apnoea.

摘要

阻塞性睡眠呼吸暂停综合征患者表现出记忆缺陷。本研究旨在探讨这种缺陷是否与记忆监测和/或记忆控制受损有关。25 名患者和 26 名健康对照者参加了一项配对联想学习任务。在参与者对每一对做出学习判断并进行初始回忆测试后,他们可以在 5 分钟内自由地重新学习他们希望的任何项目,时间长短不限。然后他们进行了第二次回忆测试。基于学习判断、项目选择和学习时间分配来评估监测和控制过程。尽管患者存在记忆障碍,但他们准确地预测了自己的回忆成绩。在复习阶段,患者优先选择判断为容易的项目,而对照组选择判断为困难的项目。然而,所有参与者都将更多的复习时间分配给了判断为困难的项目,而不是判断为容易的项目。记忆表现、元记忆过程和临床指标(即主观嗜睡、主观睡眠质量、焦虑和抑郁评分)之间没有显著相关性。结果表明,在我们的阻塞性睡眠呼吸暂停患者样本中,记忆监测和记忆控制都得到了保留。

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