La Jolla Institute for Allergy & Immunology, La Jolla, California, USA.
Curr Top Membr. 2013;71:33-58. doi: 10.1016/B978-0-12-407870-3.00002-0.
The Ca(2+) sensor STIM1 and the Ca(2+) channel ORAI1 are the fundamental working machinery of the CRAC channel, a classical pathway for store-operated Ca(2+) entry. This chapter focuses on the protein-protein interactions of STIM and ORAI proteins that control the channel.
钙（Ca2+）传感器 STIM1 和钙（Ca2+）通道 ORAI1 是 CRAC 通道的基本工作机制，也是经典的储存操纵性钙（Ca2+）内流途径。本章重点介绍控制通道的 STIM 和 ORAI 蛋白的蛋白-蛋白相互作用。
