Department of Dermatology, Chang Gung Memorial Hospital - Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Pancreatology. 2013 Jul-Aug;13(4):455-7. doi: 10.1016/j.pan.2013.03.011. Epub 2013 Mar 30.
Glucagonoma syndrome encompasses necrolytic migratory erythema (NME), hyperglucagonemia, diabetes mellitus, anemia, weight loss, glossitis, angular cheilitis, steatorrhea, diarrhea, venous thrombosis, and neuropsychiatric disturbance. Of all the symptoms, NME is a rare skin disorder which is pathognomonic for glucagonoma. We present a 61-year-old woman diagnosed initially as pancreatic head adenocarcinoma with liver metastasis prior to the skin eruption. From the dermatologic finding and other clues, glucagonoma was diagnosed finally.
胰高血糖素瘤综合征包括坏死性游走性红斑（NME）、高胰高血糖素血症、糖尿病、贫血、体重减轻、舌炎、口角炎、脂肪泻、腹泻、静脉血栓形成和神经精神障碍。在所有症状中，NME 是一种罕见的皮肤疾病，是胰高血糖素瘤的特征性表现。我们报告了一位 61 岁女性患者，在皮肤病变出现之前，最初被诊断为胰头腺癌伴肝转移。根据皮肤科发现和其他线索，最终诊断为胰高血糖素瘤。
