Suppr超能文献

[局部麻醉药的过敏反应]

[Allergic reactions to local anesthetics].

作者信息

Escolano F, Aliaga L, Alvarez J, Alcon A, Olivé A

机构信息

Hospital de l'Esperança, Barcelona.

出版信息

Rev Esp Anestesiol Reanim. 1990 May-Jun;37(3):172-5.

PMID:2389080
Abstract

We studied 35 patients which had been sent by various specialists to the Allergy department of a general hospital because they had an adverse reaction to some type of local anesthetic. The subjects underwent three types of tests: a prick test, an intradermoreaction test and a provocation test using three local anesthetics: procaine 2%, lidocaine 2%, mepivacaine 1% with no vasoconstrictors or parabens in order to rule out the possibility that the reaction was due to these substances rather than the local anaesthetic being tested. The results indicated that both the prick test and the provocation test of the local anesthetics included in the study were negative for all of the patients. One patient who had an adverse reaction to Hostacain was tested with that same anesthetic. The patient tested positive in the intradermoreaction test with a 1/10 solution but was not able to be tested with a solution free of parabens due to lack of availability. The results of our study coincide with the bibliographic research done in that real allergic reactions to local anesthetics are infrequent. The methodology used effectively distinguishes those patients with a risk of real allergic reactions there by indicating to the physician the safest local anesthetic for the patient.

摘要

我们研究了35名患者,这些患者因对某种局部麻醉剂有不良反应,由不同专科医生转诊至一家综合医院的过敏科。受试者接受了三种类型的测试:点刺试验、皮内反应试验和激发试验,使用三种局部麻醉剂:2%的普鲁卡因、2%的利多卡因、1%的甲哌卡因,均不含血管收缩剂或对羟基苯甲酸酯,以排除反应是由这些物质而非所测试的局部麻醉剂引起的可能性。结果表明,研究中所包含的局部麻醉剂的点刺试验和激发试验对所有患者均为阴性。一名对Hostacain有不良反应的患者用同一种麻醉剂进行了测试。该患者在皮内反应试验中对1/10溶液呈阳性反应,但由于无法获得不含对羟基苯甲酸酯的溶液,未能进行该溶液的测试。我们的研究结果与文献研究一致,即对局部麻醉剂的真正过敏反应很少见。所使用的方法有效地识别出有真正过敏反应风险的患者,从而为医生指明对患者最安全的局部麻醉剂。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验