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[吡咯烷酮羧酸钾在真性宫颈难产中的价值。一项双盲对照安慰剂研究]

[The value of magnesium pyrrolidone carboxylate in true cervix dystocia. A double blind versus placebo study].

作者信息

Demory J E, Firmin J M, Parot P

机构信息

CHG, Elbeuf.

出版信息

Rev Fr Gynecol Obstet. 1990 Jun;85(6):413-6.

PMID:2389112
Abstract

The efficacy of spasmolytics in cervix dystocia during labor is very contested. For this reason the authors studied the action of pyrrolidone carboxylate of magnesium for this indication in a double-blind versus placebo study (48 patients divided in two groups). Strict inclusion criteria and homogeneity of the two groups of patients allowed them to find out that the use of this particular magnesium salt reduced significantly the length of labor. Consequently the authors assess that spasmolytics work not only through their placebo effect, which is thought by some authors.

摘要

解痉药在分娩时宫颈难产中的疗效极具争议。因此,作者在一项双盲对照安慰剂研究(48例患者分为两组)中研究了镁盐吡咯烷羧酸盐在此适应症中的作用。严格的纳入标准和两组患者的同质性使他们发现,使用这种特定的镁盐可显著缩短产程。因此,作者评估解痉药不仅通过一些作者认为的安慰剂效应起作用。

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