Nat Genet. 2013 Aug;45(8):849-50. doi: 10.1038/ng.2708.
Two recent studies describe the largest molecular profiling analyses to date of clear-cell renal cell carcinoma (ccRCC) and report remarkably similar findings. The recurrent pathway alterations identified in these studies open new avenues for therapeutic advances in this chemotherapy- and radiation-resistant disease.
最近两项研究描述了迄今为止最大的透明细胞肾细胞癌(ccRCC)的分子分析,并报告了非常相似的发现。这些研究中确定的复发性途径改变为这种对化疗和放疗有抵抗力的疾病的治疗进展开辟了新的途径。