Suzuki Masashi, Ando Tetsuo, Kawakami Osamu, Sugiura Makoto, Kato Hiroko, Inagaki Tomonori
Department of Neurology, Anjo Kosei Hospital.
Rinsho Shinkeigaku. 2013;53(7):536-42. doi: 10.5692/clinicalneurol.53.536.
Intramedullary spinal cord hemorrhage (hematomyelia) is rare and usually related to trauma. Spinal vascular malformations such as intramedullary cavernomas and intradural arteriovenous malformations are the most common cause of atraumatic hematomyelia. Other considerations include warfarin or heparin anticoagulation, bleeding disorders, spinal cord tumors, and delayed complication of spinal radiation. We report the case of 48-year-old man receiving warfarin and aspirin therapy, who showed upper limb pain and dysesthesia from left axilla to left femur. Paraplegia, sensory disturbance, bladder and rectal disturbance developed gradually over two weeks, accompanied by severe back and neck pain. MRI showed hematomyelia extending from the C1 to T11 segments of the spinal cord. The hemorrhage was located mainly in the left side of the posterior column. Few cases of hematomyelia extending over 18 segments of the spinal cord have been reported. Past literature reports of hematomyelia tend to extend longitudinally above and below the area of initial hemorrhage. We thought that the shape of this hematomyelia extending longitudinally over several segments was formed by a similar pathogenesis to pencil-shaped softening of the spinal cord.
脊髓髓内出血(脊髓血肿)较为罕见,通常与外伤有关。脊髓血管畸形,如髓内海绵状血管瘤和硬脊膜内动静脉畸形,是无外伤性脊髓血肿最常见的原因。其他需要考虑的因素包括华法林或肝素抗凝、出血性疾病、脊髓肿瘤以及脊髓放疗的延迟并发症。我们报告了一例48岁接受华法林和阿司匹林治疗的男性病例,该患者表现出从左腋窝到左大腿的上肢疼痛和感觉异常。截瘫、感觉障碍、膀胱和直肠功能障碍在两周内逐渐发展,伴有严重的背部和颈部疼痛。MRI显示脊髓血肿从C1延伸至T11节段。出血主要位于后柱左侧。很少有脊髓血肿延伸超过18个脊髓节段的病例报道。既往关于脊髓血肿的文献报道倾向于在初始出血区域的上下纵向延伸。我们认为这种在几个节段上纵向延伸的脊髓血肿的形态是由与铅笔状脊髓软化相似的发病机制形成的。