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神经危重症患者的疼痛管理。

Pain management in neurocritical care.

机构信息

Department of Neurology, VU Medical Center, De Boelelaan 1117, Amsterdam, The Netherlands,

出版信息

Neurocrit Care. 2013 Oct;19(2):232-56. doi: 10.1007/s12028-013-9851-0.

DOI:10.1007/s12028-013-9851-0
PMID:23893074
Abstract

The core challenge of pain management in neurocritical care is to keep the patient comfortable without masking or overlooking any neurological deterioration. Clearly in patients with a neurological problem there is a conflict of clinical judgement and adequate pain relief. Here we review the presentation, assessment, and development of pain in the clinical spectrum of patients with associated neurological problems seen in a general intensive care setting. Many conditions predispose to the development of chronic pain. There is evidence that swift and targeted pain management may improve the outcome. Importantly pain management is multidisciplinary. The available non-invasive, pharmacological, and invasive treatment strategies are discussed.

摘要

神经危重症患者的疼痛管理的核心挑战是在不掩盖或忽视任何神经恶化的情况下让患者感到舒适。显然,对于存在神经问题的患者,临床判断和充分的疼痛缓解之间存在冲突。在这里,我们回顾了在普通重症监护病房中遇到的伴有神经问题的患者的临床谱中疼痛的表现、评估和发展。许多情况会导致慢性疼痛的发生。有证据表明,迅速和有针对性的疼痛管理可以改善预后。重要的是,疼痛管理是多学科的。讨论了可用的非侵入性、药物和侵入性治疗策略。

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Steroids for preventing recurrence of acute severe migraine headaches: a meta-analysis.预防急性重度偏头痛发作的类固醇:一项荟萃分析。
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Pain and multiple sclerosis: pathophysiology and treatment.疼痛与多发性硬化症:病理生理学与治疗。
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An open-label extension study to investigate the long-term safety and tolerability of THC/CBD oromucosal spray and oromucosal THC spray in patients with terminal cancer-related pain refractory to strong opioid analgesics.一项开放性标签扩展研究,旨在调查 THC/CBD 口腔黏膜喷雾和口腔黏膜 THC 喷雾在强阿片类镇痛药难治性终末期癌症相关疼痛患者中的长期安全性和耐受性。
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