感觉神经元病（神经节病）中 S1 神经根刺激引起的腓肠肌近段诱发 H 反射。
Proximally evoked soleus H-reflex to S1 nerve root stimulation in sensory neuronopathies (ganglionopathies).
机构信息
Department of Neurology, Huashan Hospital, Fudan University, 12 Mid-Wulumuqi Road, Shanghai, 200040, China.
出版信息
Muscle Nerve. 2013 Nov;48(5):814-6. doi: 10.1002/mus.23975. Epub 2013 Oct 12.
INTRODUCTION
Sensory neuronopathy (SNN) mimics distal sensory axonopathy. The conventional H-reflex elicited by tibial nerve stimulation (tibial H-reflex) is usually abnormal in both conditions. We evaluated the proximally evoked soleus H-reflex in response to S1 nerve root stimulation (S1 foramen H-reflex) in SNN.
METHODS
Eleven patients with SNN and 6 with distal sensory axonopathy were studied. Tibial and S1 foramen H-reflexes were performed bilaterally in each patient.
RESULTS
Tibial and S1 foramen H-reflexes were absent bilaterally in all patients with SNN. In the patients with distal sensory axonopathy, tibial H-reflexes were absent in 4 and demonstrated prolonged latencies in 2, but S1 foramen H-reflexes were normal.
CONCLUSIONS
Characteristic absence of the H-reflex after both proximal and distal stimulation reflects primary loss of dorsal root ganglion (DRG) neurons and the distinct non-length-dependent impairment of sensory nerve fibers in SNN.
简介
感觉神经元病（SNN）类似于远端感觉轴索性神经病。两种情况下，由胫神经刺激引发的常规 H 反射（胫神经 H 反射）通常都是异常的。我们评估了对 S1 神经根刺激（S1 孔 H 反射）诱发的比目鱼肌近端 H 反射在 SNN 中的情况。
方法
研究了 11 例 SNN 患者和 6 例远端感觉轴索性神经病患者。每位患者均进行双侧胫神经和 S1 孔 H 反射检查。
结果
所有 SNN 患者双侧胫神经和 S1 孔 H 反射均完全消失。在远端感觉轴索性神经病患者中，4 例患者的胫神经 H 反射消失，2 例患者的潜伏期延长，但 S1 孔 H 反射正常。
结论
近端和远端刺激后 H 反射均完全消失反映了背根神经节（DRG）神经元的原发性丧失以及 SNN 中感觉神经纤维的明显非长度依赖性损害。
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