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The immunosuppressive agent 15-deoxyspergualin induces tolerance and modulates MHC-antigen expression and interleukin-1 production in the early phase of rat allograft responses.

作者信息

Waaga A M, Ulrichs K, Krzymanski M, Treumer J, Hansmann M L, Rommel T, Müller-Ruchholtz W

机构信息

Department of Immunology, Medical School, University of Kiel, FRG.

出版信息

Transplant Proc. 1990 Aug;22(4):1613-4.

PMID:2389421
Abstract
摘要

相似文献

1
The immunosuppressive agent 15-deoxyspergualin induces tolerance and modulates MHC-antigen expression and interleukin-1 production in the early phase of rat allograft responses.免疫抑制剂15-脱氧精胍菌素在大鼠同种异体移植反应的早期阶段诱导耐受并调节MHC抗原表达和白细胞介素-1的产生。
Transplant Proc. 1990 Aug;22(4):1613-4.
2
Induction of specific tolerance by 15-deoxyspergualin (DOS) treatment after rat skin and kidney transplantation in rats. Analysis of effectivity of various protocols of DOS application.大鼠皮肤和肾脏移植后经15-去氧精胍菌素（DOS）处理诱导特异性耐受。DOS不同应用方案的有效性分析。
Arch Immunol Ther Exp (Warsz). 1996;44(2-3):143-53.
3
Treatment of acute rejection episodes and induction of tolerance in rat skin allotransplantation by 15-deoxyspergualin.15-脱氧精胍菌素对大鼠皮肤同种异体移植急性排斥反应的治疗及免疫耐受的诱导
Transplant Proc. 1990 Aug;22(4):1626-30.
4
Impact of 15-deoxyspergualin on MHC class I and II antigen expression following small bowel transplantation in rats.15-脱氧精胍菌素对大鼠小肠移植后MHC I类和II类抗原表达的影响
Transplant Proc. 1994 Jun;26(3):1592-3.
5
KRP-203, a novel synthetic immunosuppressant, prolongs graft survival and attenuates chronic rejection in rat skin and heart allografts.新型合成免疫抑制剂KRP - 203可延长大鼠皮肤和心脏同种异体移植的移植物存活时间并减轻慢性排斥反应。
Circulation. 2005 Jan 18;111(2):222-9. doi: 10.1161/01.CIR.0000152101.41037.AB. Epub 2005 Jan 10.
6
15-deoxyspergualin downregulates MHC class II antigen expression and cell migration in models of graft-versus-host and host-versus-graft disease.15-脱氧精胍菌素在移植物抗宿主病和宿主抗移植物病模型中下调MHC II类抗原表达及细胞迁移。
Transplant Proc. 1996 Oct;28(5):2515-7.
7
T-cell recognition of donor class I major histocompatibility complex peptides during allograft rejection.
Transplant Proc. 1993 Feb;25(1 Pt 1):187-8.
8
Influence of a rat kidney perfusion using the anti-MHC class II monoclonal antibody and reduced dose of 15-deoxyspergualine on the allogeneic graft survival.使用抗II类主要组织相容性复合体单克隆抗体和降低剂量的15-脱氧精胍菌素对大鼠肾脏进行灌注对同种异体移植物存活的影响。
Arch Immunol Ther Exp (Warsz). 1995;43(5-6):293-7.
9
Histologic and immunohistochemical evaluation of deoxyspergualin-treated rat renal transplants.去氧精胍菌素处理的大鼠肾移植组织学及免疫组化评估
Transplant Proc. 1992 Aug;24(4):1633-4.
10
Flow cytometric analysis of graft-infiltrating lymphocytes in deoxyspergualin-treated rat renal transplants.脱氧精胍菌素处理的大鼠肾移植中移植物浸润淋巴细胞的流式细胞术分析
Transplant Proc. 1994 Aug;26(4):1905-6.

引用本文的文献

1
Deoxyspergualin preferentially inhibits the growth and maturation of anti-CD40-activated surface IgD+ B lymphocytes.去氧精胍菌素优先抑制抗CD40激活的表面IgD+B淋巴细胞的生长和成熟。
Clin Exp Immunol. 1998 Jun;112(3):495-500. doi: 10.1046/j.1365-2249.1998.00602.x.
2
The immunosuppressant 15-deoxyspergualin [correction of 1,5-deoxyspergualin] reveals commonality between preT and preB cell differentiation.免疫抑制剂15-脱氧精胍菌素[纠正为1,5-脱氧精胍菌素]揭示了前T细胞和前B细胞分化之间的共性。
J Exp Med. 1996 Jun 1;183(6):2427-36. doi: 10.1084/jem.183.6.2427.
3
Impact of 15-deoxyspergualin on effector cells in experimental autoimmune diseases of the nervous system in the Lewis rat.
15-脱氧精胍菌素对Lewis大鼠实验性自身免疫性神经系统疾病中效应细胞的影响
Clin Exp Immunol. 1994 Dec;98(3):494-502. doi: 10.1111/j.1365-2249.1994.tb05518.x.