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当前主动脉瓣置换术的发展趋势:快速部署 EDWARDS INTUITY 瓣膜系统的研发。

Current trends in aortic valve replacement: development of the rapid deployment EDWARDS INTUITY valve system.

机构信息

Leipzig Heart Center, University of Leipzig, Struempellstrasse 39, 04289 Leipzig, Germany.

出版信息

Expert Rev Med Devices. 2013 Jul;10(4):461-70. doi: 10.1586/17434440.2013.811828.

Abstract

Although conventional aortic valve replacement (AVR) surgery remains the gold standard for patients with aortic stenosis, transcutaneous aortic valve replacement is becoming increasingly common in high-risk patients. The techniques of minimal invasive surgery (MIS) have been well known for many years, but MIS is applied in a disappointingly low percentage of patients undergoing AVR surgery. The EDWARDS INTUITY rapid deployment aortic valve system is designed to facilitate the performance of MIS AVR surgery. In addition, the reduced implantation times may be beneficial in higher risk patients or those requiring concomitant procedures. The system combines established pericardial valve technology with modern stent expertise obtained from the transcutaneous aortic valve replacement experience. Preliminary results from a multicenter trial have shown low rates of morbidity and mortality, and excellent hemodynamic performance. The EDWARDS INTUITY promises to be an exciting device that may further change the landscape of aortic valve intervention.

摘要

虽然传统的主动脉瓣置换术(AVR)仍然是主动脉瓣狭窄患者的金标准,但经皮主动脉瓣置换术在高危患者中越来越常见。微创外科(MIS)技术已为人熟知多年,但在接受 AVR 手术的患者中,MIS 的应用比例却低得令人失望。EDWARDS INTUITY 快速部署主动脉瓣系统旨在促进 MIS AVR 手术的开展。此外,植入时间的缩短可能对高风险患者或需要同时进行其他手术的患者有益。该系统结合了已确立的心包瓣技术和从经皮主动脉瓣置换经验中获得的现代支架专业知识。来自多中心试验的初步结果显示发病率和死亡率低,血液动力学性能优异。EDWARDS INTUITY 有望成为一种令人兴奋的器械,可能会进一步改变主动脉瓣介入治疗的格局。

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