Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, BS-10/1, Sector 10, Jankipuram extension, Sitapur Road, PO Box 173, Lucknow 226031, India.
Curr Top Med Chem. 2013 Aug;13(16):2011-25. doi: 10.2174/15680266113139990126.
Thiourea and guanidine substructural units are of significant importance as the compounds containing these core units either in the open or the cyclic form are known to display an array of pharmacological properties. This brief review assimilates the literature on the medicinal significance of thiourea and guanidine derivatives with respect to antimalarial and antimicrobial activities.
硫脲和胍亚基单元非常重要，因为含有这些核心单元的化合物无论是开链形式还是环状形式，都具有一系列的药理学特性。这篇简短的综述综合了有关硫脲和胍衍生物在抗疟疾和抗菌活性方面的医学意义的文献。
