眼眶环状肉芽肿作为系统性结节病的表现。
Orbital granuloma annulare as presentation of systemic sarcoidosis.
作者信息
Kang Joann J, Aakalu Vinay K, Lin Amy, Setabutr Pete
机构信息
Department of Ophthalmology and Visual Sciences and.
出版信息
Orbit. 2013 Dec;32(6):372-4. doi: 10.3109/01676830.2013.812125. Epub 2013 Jul 29.
PURPOSE
To report a unique case of an orbital mass with atypical histopathologic features that although overlap with other granulomatous disorders, likely represents orbital involvement of systemic sarcoidosis.
METHODS
Observational case report.
RESULTS
A 51-year-old woman presented with an orbital mass and was found to have mild proptosis and restriction of ocular motility. The remainder of her ophthalmic exam was unremarkable. Excisional biopsy revealed ill-defined granulomas with central necrosis, chronic inflammation and sclerotic collagen; several features consistent with granuloma annulare. Further systemic workup including laboratory and radiologic studies were compatible with a diagnosis of systemic sarcoidosis.
CONCLUSION
Our case emphasizes the importance of a complete systemic workup with the detection of an orbital granuloma to ensure accurate diagnosis and appropriate management.
目的
报告一例具有非典型组织病理学特征的眼眶肿物病例，该病例虽与其他肉芽肿性疾病有重叠表现，但可能为系统性结节病累及眼眶。
方法
观察性病例报告。
结果
一名51岁女性因眼眶肿物就诊，发现有轻度眼球突出及眼球运动受限。眼科检查的其他方面未见异常。切除活检显示边界不清的肉芽肿，伴有中央坏死、慢性炎症和硬化性胶原；有几个特征与环状肉芽肿一致。包括实验室和影像学检查在内的进一步全身检查结果与系统性结节病的诊断相符。
结论
我们的病例强调了对眼眶肉芽肿进行全面全身检查以确保准确诊断和恰当治疗的重要性。
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