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损伤控制和开放性腹部手术在战斗中的应用。

Use of damage control and the open abdomen in combat.

作者信息

Bograd Benjamin, Rodriguez Carlos, Amdur Richard, Gage Fred, Elster Eric, Dunne James

机构信息

Department of Surgery, Walter Reed National Military Medical Center, Bethesda, Maryland, USA.

出版信息

Am Surg. 2013 Aug;79(8):747-53.

Abstract

Despite the well-documented use of damage control laparotomy (DCL) in civilian trauma, its use has not been well described in the combat setting. Therefore, we sought to document the use of DCL and to investigate its effect on patient outcome. Prospective data were collected on 1603 combat casualties injured between April 2003 and January 2009. One hundred seventy patients (11%) underwent an exploratory laparotomy (ex lap) in theater and comprised the study cohort. DCL was defined as an abbreviated ex lap resulting in an open abdomen. Patients were stratified by age, Injury Severity Score (ISS), Glasgow Coma Score (GCS), mechanism of injury, and blood product administration. Multivariate regression analyses were used to determine risks factors for intensive care unit length of stay (ICU LOS), hospital length of stay (HLOS), and the need for DCL. Mean age of the cohort was 24 ± 5 years, ISS was 21 ± 11, and 94 per cent sustained penetrating injury. Patients with DCL comprised 50.6 per cent (n = 86) of the study cohort and had significant increases in ICU admission (P < 0.001), ICU LOS (P < 0.001), HLOS (P < 0.05), ventilator days (P < 0.001), abdominal complications (P < 0.05), but not mortality (P = 0.65) compared with patients without DCL. When compared with the non-DCL group, patients undergoing DCL required significantly more blood products (packed red blood cells, fresh-frozen plasma, platelets, and cryoprecipitate; P < 0.001). Multivariate regression analyses revealed blood transfusion and GCS as significant risk factors for DCL (P < 0.05). Patients undergoing DCL had increased complications and resource use but not mortality compared with patients not undergoing DCL. The need for combat DCL may be different compared with civilian use. Prospective studies to evaluate outcomes of DCL are warranted.

摘要

尽管损伤控制剖腹术(DCL)在 civilian 创伤中的应用已有充分记录,但其在战斗环境中的使用情况尚未得到充分描述。因此,我们试图记录 DCL 的使用情况,并研究其对患者预后的影响。收集了 2003 年 4 月至 2009 年 1 月期间 1603 名战斗伤员的前瞻性数据。170 名患者(11%)在战区接受了剖腹探查术(ex lap),构成了研究队列。DCL 被定义为导致腹部开放的简化 ex lap。患者按年龄、损伤严重程度评分(ISS)、格拉斯哥昏迷评分(GCS)、损伤机制和血液制品输注情况进行分层。多变量回归分析用于确定重症监护病房住院时间(ICU LOS)、医院住院时间(HLOS)和 DCL 需要的危险因素。队列的平均年龄为 24±5 岁,ISS 为 21±11,94%为穿透伤。接受 DCL 的患者占研究队列的 50.6%(n = 86),与未接受 DCL 的患者相比,ICU 入院率(P < 0.001)、ICU LOS(P < 0.001)、HLOS(P < 0.05)、呼吸机使用天数(P < 0.001)、腹部并发症(P < 0.05)显著增加,但死亡率无显著差异(P = 0.65)。与非 DCL 组相比,接受 DCL 的患者需要显著更多的血液制品(浓缩红细胞、新鲜冰冻血浆、血小板和冷沉淀;P < 0.001)。多变量回归分析显示输血和 GCS 是 DCL 的显著危险因素(P < 0.05)。与未接受 DCL 的患者相比,接受 DCL 的患者并发症和资源使用增加,但死亡率无差异。战斗环境中 DCL 的需求可能与 civilian 使用情况不同。有必要进行前瞻性研究以评估 DCL 的预后。

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