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脑动静脉畸形的诊断与治疗。

The diagnosis and management of brain arteriovenous malformations.

机构信息

Neuroradiology Division, Department of Radiology, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9178, USA.

出版信息

Neurol Clin. 2013 Aug;31(3):749-63. doi: 10.1016/j.ncl.2013.03.003. Epub 2013 Apr 17.

DOI:10.1016/j.ncl.2013.03.003
PMID:23896503
Abstract

Although uncommon in the general population, cerebral arteriovenous malformations (AVMs) can pose a significant health risk if a rupture occurs. Advances in noninvasive imaging have led to an increase in the identification of unruptured AVMs, presenting new challenges in management, given their poorly understood natural history. Over the past decade, there have been significant developments in the management and treatment of intracranial AVMs. This article discusses the pathophysiology, natural history, clinical presentations, and current treatment options, including multimodal approaches, for these vascular malformations.

摘要

尽管在一般人群中不常见,但如果发生破裂,脑动静脉畸形(AVM)可能会带来重大健康风险。由于对其自然史了解甚少,非侵入性成像技术的进步导致未破裂 AVM 的识别率增加,这给管理带来了新的挑战。在过去的十年中,颅内 AVM 的管理和治疗取得了重大进展。本文讨论了这些血管畸形的病理生理学、自然史、临床表现和当前的治疗选择,包括多模式方法。

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