Pilar Bravo M, Castellanos E, del Rey Calero J
Departamento de Medicina Preventiva y Salud Pública, Facultad de Medicina, Universidad Autónoma de Madrid, España.
Arch Esp Urol. 1990 Jun;43(5):511-4.
An epidemiological case-control study was performed to know the factors involved in the development of prostatic cancer. Ninety patients diagnosed of prostatic cancer in La Paz Hospital (Madrid) from January, 1981 to December, 1987, comprised the study group. The controls were 180 male patients from the same hospital and with no personal or familial antecedents of urologic disease or malignant tumours. The cases and controls were matched by age, and year of admission to the hospital. The results of the study revealed that the disease is strongly associated to familial antecedents of prostatic cancer. The risk for the patients with these antecedents is 3.14. The disease was statistically associated to a fatherhood of more than 5 children. No association between the disease and antecedents of tonsillectomy, rheumatic fever, educational level, place of residence, or marital status was found.
开展了一项流行病学病例对照研究,以了解前列腺癌发病的相关因素。1981年1月至1987年12月在拉巴斯医院(马德里)确诊的90例前列腺癌患者组成了研究组。对照组为来自同一家医院的180名男性患者,他们没有泌尿系统疾病或恶性肿瘤的个人或家族病史。病例和对照按照年龄以及入院年份进行匹配。研究结果显示,该疾病与前列腺癌家族病史密切相关。有这些家族病史的患者患病风险为3.14。该疾病在统计学上与生育5个以上孩子相关。未发现该疾病与扁桃体切除术史、风湿热、教育程度、居住地点或婚姻状况之间存在关联。