Horn J, Michalek F, Tzschucke C C, Bannwarth W
Institut für Organische Chemie und Biochemie, Albert-Ludwigs-Universität Freiburg, Albertstr. 21, Freiburg, 79104, Germany.
Top Curr Chem. 2004;242:43-75. doi: 10.1007/b96873.
Catalysts immobilized on solid supports have become valuable tools for simplified product isolation and catalyst recycling. An alternative to covalent attachment to a solid support is to immobilize catalysts by non-covalent bonding through hydrogen bridges, or ionic, hydrophobic or fluorous interactions. Compared to covalent attachment, such non-covalent approaches increase the flexibility in the choice of the support material, reaction conditions and work-up strategies. Numerous catalytic reactions employing one of these non-covalent bonding strategies have meanwhile appeared in the literature.
固定在固体载体上的催化剂已成为实现简化产物分离和催化剂循环利用的重要工具。与共价连接到固体载体不同的一种方法是通过氢键、离子、疏水或氟代相互作用以非共价键合的方式固定催化剂。与共价连接相比，这种非共价方法在载体材料、反应条件和后处理策略的选择上增加了灵活性。同时，文献中已出现了许多采用这些非共价键合策略之一的催化反应。
