McVeigh Katherine, Cornish Kurt Spiteri, Reddy Aravind R, Vakros Georgios
Eye Clinic, Royal United Bath Hospital, Bath, UK ; Ophthalmology Department, Aberdeen Royal Infirmary, Aberdeen, United Kingdom.
Clin Ophthalmol. 2013;7:1511-4. doi: 10.2147/OPTH.S45161. Epub 2013 Jul 23.
To report a case of retained Descemet's membrane following penetrating keratoplasty in a patient suffering from Fuchs' endothelial corneal dystrophy. The use of confocal microscopy, histopathological tissue analysis, and treatment options are discussed.
Case report of an 85-year-old man with a past ophthalmic history of atrophic macular degeneration, underwent a penetrating keratoplasty for Fuchs' endothelial corneal dystrophy. Postoperative review revealed a retained retrocorneal membrane within the anterior chamber. Further surgery was performed to excise the membrane, with a subjective and objective postoperative improvement in visual acuity and without subsequent complications of the corneal graft.
Histopathological assessment confirmed the clinical suspicion of a retained Descemet's membrane, marrying with the initial histology from the corneal button excised during the penetrating keratoplasty, which showed only a very thin Descemet's layer.
Retention of the Descemet's membrane following penetrating keratoplasty is a rare but potential complication of this surgery, particularly in cases of Fuchs' endothelial corneal dystrophy due to the thickened and abnormal histological nature of the endothelium and high index of suspicion is required.
报告1例患有富克斯内皮角膜营养不良的患者在穿透性角膜移植术后出现后弹力层膜残留的病例。讨论共焦显微镜检查、组织病理学分析及治疗方案的应用。
报告1例85岁男性患者,既往有萎缩性黄斑变性眼科病史,因富克斯内皮角膜营养不良接受穿透性角膜移植术。术后复查发现前房内有后弹力层膜残留。进一步手术切除该膜,术后视力在主观和客观上均有改善,且角膜移植未出现后续并发症。
组织病理学评估证实了临床对后弹力层膜残留的怀疑,与穿透性角膜移植术中切除的角膜植片最初的组织学检查结果相符,后者仅显示非常薄的后弹力层。
穿透性角膜移植术后后弹力层膜残留是该手术一种罕见但可能出现的并发症,尤其是在富克斯内皮角膜营养不良的病例中,因为内皮的组织学性质增厚且异常,需要高度怀疑。