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Collaborative multicenter trials in Latin America: challenges and opportunities in orthopedic and trauma surgery.

作者信息

Moraes Vinicius Ynoe de, Belloti Joao Carlos, Faloppa Flavio, Bhandari Mohit

机构信息

Department of Orthopedics and Traumatology, Escola Paulista de Medicina, Universidade Federal de São Paulo, Brazil.

出版信息

Sao Paulo Med J. 2013;131(3):187-92. doi: 10.1590/1516-3180.2013.1313555.

DOI:10.1590/1516-3180.2013.1313555
PMID:23903268
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10852115/
Abstract

CONTEXT AND OBJECTIVE Orthopedic research agendas should be considered from a worldwide perspective. Efforts should be planned as the means for obtaining evidence that is valid for health promotion with global outreach. DESIGN AND SETTING Exploratory study conducted at Universidade Federal de São Paulo (Unifesp), São Paulo, Brazil, and McMaster University, Hamilton, Canada. METHODS We identified and analyzed collaborative and multicenter research in Latin America, taking into account American and Canadian efforts as the reference points. We explored aspects of the data available from official sources and used data from traffic accidents as a model for discussing collaborative research in these countries. RESULTS The evaluation showed that the proportion of collaborative and multicenter studies in our setting is small. A brief analysis showed that the death rate due to traffic accidents is very high. Thus, it seems clear to us that initiatives involving collaborative studies are important for defining and better understanding the patterns of injuries resulting from orthopedic trauma and the forms of treatment. Orthopedic research may be an important tool for bringing together orthopedic surgeons, researchers and medical societies for joint action. CONCLUSIONS We have indicated some practical guidelines for initiatives in collaborative research and have proposed some solutions with a summarized plan of action for conducting evidence-based research involving orthopedic trauma.

摘要

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本文引用的文献

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RANDOMIZED CONTROLLED TRIALS IN ORTHOPEDICS AND TRAUMATOLOGY: SYSTEMATIC ANALYSIS ON THE NATIONAL EVIDENCE.骨科与创伤学中的随机对照试验:基于国家证据的系统分析
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Multi-investigator collaboration in orthopaedic surgery research compared to other medical fields.骨科手术研究中的多机构合作与其他医学领域相比。
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The epidemiology of open fractures in adults. A 15-year review.
骨科与创伤学的治疗结果:将研究转化为临床实践
Acta Ortop Bras. 2014;22(6):330-3. doi: 10.1590/1413-78522014220601009.
成人开放性骨折的流行病学。一项 15 年的回顾。
Injury. 2012 Jun;43(6):891-7. doi: 10.1016/j.injury.2011.12.007. Epub 2011 Dec 27.
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Challenges and barriers to improving care of the musculoskeletal patient of the future - a debate article and global perspective.改善未来肌肉骨骼疾病患者护理的挑战与障碍——一篇辩论文章及全球视角
Patient Saf Surg. 2011 Sep 25;5:23. doi: 10.1186/1754-9493-5-23.
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Hierarchy of evidence relating to hand surgery in Brazilian orthopedic journals.巴西骨科期刊中与手外科相关的证据等级
Sao Paulo Med J. 2011 Mar;129(2):94-8. doi: 10.1590/s1516-31802011000200007.
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Clinical trials in orthopaedics research. Part I. Cultural and practical barriers to randomized trials in orthopaedics.骨科研究中的临床试验。第一部分。骨科随机试验的文化和实际障碍。
J Bone Joint Surg Am. 2011 Mar 2;93(5):e15. doi: 10.2106/JBJS.J.00229.
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Global burden of trauma: Need for effective fracture therapies.全球创伤负担:对有效骨折治疗方法的需求。
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Resolving controversies in hip fracture care: the need for large collaborative trials in hip fractures.解决髋部骨折护理中的争议:髋部骨折大型协作试验的必要性。
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Lancet. 2009 Apr 4;373(9670):1175-82. doi: 10.1016/S0140-6736(09)60447-5. Epub 2009 Mar 28.