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[体重和急性肠系膜缺血持续时间对接受肠道血管重建大鼠死亡率的影响]

[Effect of body weight and acute mesenteric ischemia duration on the mortality of rats subjected to intestinal revascularization].

作者信息

Ortiz Lacorzana J, García-Alonso Montoya I, Portugal Porras V, Méndez Martín J

机构信息

Cátedra de Patología y Clínica Quirúrgicas (Laboratorio de Cirugía Experimental), Facultad de Medicina y Ondontología, Universidad del País Vasco.

出版信息

Rev Esp Enferm Dig. 1990 Apr;77(4):263-7.

PMID:2390341
Abstract

We have studied the influence of corporal weight and acute mesenteric ischemia (AMI) duration on the mortality and average survival of rats submitted to intestinal revascularization. The results demonstrated that mortality is under 50% when the AMI is equal or less than 2 hours. There are also important differences in mortality, for the same AMI duration, depending on the corporal weight and age of the animals. The differences are statistically significant up to 210 g. In conclusion, in experimental studies on intestinal ischemia-revascularization, it is necessary to correct for factors as ischemia duration and weight, which are variables that can alter the results.

摘要

我们研究了体重和急性肠系膜缺血(AMI)持续时间对接受肠道血管重建的大鼠死亡率和平均存活时间的影响。结果表明,当AMI等于或小于2小时时,死亡率低于50%。对于相同的AMI持续时间,根据动物的体重和年龄,死亡率也存在重要差异。在体重达210克之前,这些差异具有统计学意义。总之,在肠道缺血-血管重建的实验研究中,有必要校正缺血持续时间和体重等因素,这些变量会改变实验结果。

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