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[小肠急性缺血及缺血后时期的微循环障碍]

[Microcirculatory disorders in acute ischemia of the small intestine and in the postischemic period].

作者信息

Shinkarenko V S, Collantes J J

出版信息

Patol Fiziol Eksp Ter. 1989 Jul-Aug(4):49-52.

PMID:2594430
Abstract

Microcirculation in the small intestine of rats during ischemia (from 5 to 240 minutes) and in the period of reperfusion (from 60 minutes to 10 days) was studied by biomicroscopy. Ischemia was modelled by ligating the base of the intestinal loop. Sharp microhemodynamic disorders occurred during ischemia, compensatory mechanisms intensifying the blood flow were switched on, the microvascular channel, including vessels which previously did not function, were dilated. Mechanisms concerned with redistribution of fluid in the intra- and perivascular space were evidently the underlying factors of capillary dilatation. In the late-term periods of reperfusion ischemia leads to increase of the number of microvessels in the ischemic part of the organ.

摘要

通过活体显微镜研究了大鼠小肠在缺血(5至240分钟)及再灌注期(60分钟至10天)的微循环。通过结扎肠袢基部模拟缺血。缺血期间出现明显的微血流动力学紊乱,启动了增强血流的代偿机制,包括先前不起作用的血管在内的微血管通道扩张。血管内和血管周围空间液体重新分布的机制显然是毛细血管扩张的潜在因素。在再灌注后期,缺血导致器官缺血部分微血管数量增加。

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