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[胰腺囊性乳头状瘤。1例病例报告及文献复习]

[Cystic papillary tumor of the pancreas. Presentation of a case and review of the literature].

作者信息

Suárez Peñaranda J M, Capdevila Puerta A, Castro Pérez J M, Machuca Santacruz J

机构信息

Servicio de Anatomía Patológica, Hospital Juan Canalejo, La Coruña.

出版信息

Rev Esp Enferm Dig. 1990 Apr;77(4):301-4.

PMID:2390347
Abstract

Cystic papillary tumor is an uncommon neoplasia of the pancreas; there are about 150 cases reported in the literature. It is usually encountered in young females and its clinical course is almost always benign, although with frequent recurrences and, exceptionally, metastases. The clinical presentation is non specific; the recommended treatment is surgical resection, which has excellent results. The pathologic findings, gross and microscopic, are quite characteristic: alternating solid, papillary and cystic areas. On the other hand, there is no agreement on the histogenesis of the tumor; the results of ultrastructural and immunohistochemical studies are not consistent. We present a case of cystic papillary tumor of the pancreas in a 58 year-old female, including histochemical and ultrastructural findings and a review of the clinical and pathological data reported in the literature. As the histochemical and ultrastructural findings are non specific, we believe, according to recent opinions, that this tumor could originate in a very primitive cell, able to differentiate to endocrine or exocrine elements, almost always incompletely.

摘要

囊性乳头状瘤是一种罕见的胰腺肿瘤;文献报道约有150例。它通常见于年轻女性,其临床病程几乎总是良性的,尽管常有复发,极少数情况下会发生转移。临床表现不具特异性;推荐的治疗方法是手术切除,效果良好。大体和显微镜下的病理表现颇具特征:实性、乳头状和囊性区域交替出现。另一方面,关于该肿瘤的组织发生尚无定论;超微结构和免疫组化研究结果并不一致。我们报告一例58岁女性胰腺囊性乳头状瘤病例,包括组织化学和超微结构 findings以及对文献报道的临床和病理数据的回顾。由于组织化学和超微结构 findings不具特异性,我们根据最近的观点认为,这种肿瘤可能起源于一种非常原始的细胞,能够分化为内分泌或外分泌成分,但几乎总是不完全分化。 (注:原文中“findings”未翻译完整,可能是有遗漏信息,可补充完整后再准确翻译。)

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