Tatsuta Tetsuya, Yoshimura Tetsuro, Hasui Keisuke, Takasugi Kaori, Sawaya Manabu, Hanabata Norihiro, Shimoyama Tadashi, Kijima Hiroshi, Fukuda Shinsaku
Department of Gastroenterology, Hirosaki University Graduate School of Medicine, Japan.
Intern Med. 2013;52(15):1697-701. doi: 10.2169/internalmedicine.52.0083. Epub 2012 Mar 1.
A 60-year-old woman was admitted for the treatment of a gastric neuroendocrine tumor (NET) associated with type A chronic atrophic gastritis. The lesion measured 10 mm in diameter, and a computed tomography scan did not reveal any metastatic lesions. Endoscopic submucosal dissection (ESD) was subsequently performed. A histological examination revealed three gastric NETs, two of which exhibited vessel invasion. Endocrine cell micronests associated with a high risk of recurrence were also observed. Therefore, the patient underwent total gastrectomy with lymph node dissection. Because vessel invasion can occur in patients with small gastric NET G1, the use of ESD should be considered to carefully estimate the presence of invasion.
一名60岁女性因治疗与A型慢性萎缩性胃炎相关的胃神经内分泌肿瘤（NET）入院。病变直径为10毫米，计算机断层扫描未发现任何转移病灶。随后进行了内镜下黏膜下剥离术（ESD）。组织学检查发现三个胃NET，其中两个表现出血管侵犯。还观察到与高复发风险相关的内分泌细胞微巢。因此，患者接受了全胃切除术及淋巴结清扫术。由于小胃NET G1患者可能发生血管侵犯，应考虑使用ESD仔细评估是否存在侵犯。
