Hernandez-Vasquez A, Will J A, Quay W B
Cell Tissue Res. 1978 Jan 17;186(2):203-7. doi: 10.1007/BF00225531.
The neuroepithelial bodies (NEB's) of the lung of 29-day-old fetuses and 1-day-old rabbits, under the conditions of this study, neither take up 3H-thymidine nor undergo mitosis. Also the NEB's are not derived at these times from proliferations of other kinds of epithelial cells in the intrapulmonary airways. It is, therefore, suggested that the difference in numbers of NEB's previously observed by us, between the 29-day fetus and the 1-day-old rabbit, is due either to regranulation or acquisition of argyrophilic material by the NEB's or differentiation of other epithelial types. It is concluded that the NEB's are composed of well differentiated cells, which have a greatly reduced capacity to undergo mitosis.
在本研究条件下,29日龄胎儿和1日龄兔肺中的神经上皮小体(NEB)既不摄取3H-胸腺嘧啶核苷,也不进行有丝分裂。此外,在这些时期,NEB并非源自肺内气道中其他类型上皮细胞的增殖。因此,我们认为之前观察到的29日龄胎儿和1日龄兔之间NEB数量的差异,要么是由于NEB重新形成颗粒或获得嗜银物质,要么是其他上皮类型的分化所致。结论是,NEB由高度分化的细胞组成,其进行有丝分裂的能力大大降低。