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确定前庭神经鞘瘤听力保留手术的基准。

Determining benchmarks in hearing preservation surgery for vestibular schwannoma.

作者信息

Gluth Michael B, Day John D, Dornhoffer John L

机构信息

Department of Otolaryngology-Head and Neck Surgery, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States.

出版信息

J Neurol Surg B Skull Base. 2012 Aug;73(4):273-80. doi: 10.1055/s-0032-1312710.

Abstract

Objectives The objectives of this study were to determine minimal benchmarks of success in vestibular schwannoma hearing preservation surgery, wherein the likelihood of having preserved hearing in a single patient is at least as likely as having created a poor facial nerve outcome for a single patient. Design This is a statistical analysis of published literature. Setting Academic Tertiary Medical Center. Main Outcome Measures Based on published natural history data, the number needed to treat (NNT) equation was used to calculate the minimally acceptable hearing preservation rates within various hearing classification schemes. Results Given good facial nerve outcome rates of 85, 90, and 95%, the corresponding hearing preservation rates at 4.7 years that are likely to preserve classes A and B hearing (American Academy of Otolaryngology-Head and Neck Surgery classification) in a single patient as to cause a poor facial nerve outcome are 70, 65, and 60%, respectively. If surgery is limited exclusively to intracanalicular tumors, these rates drop to 62, 57, and 52%, respectively. If the word recognition scoring classification is used, required hearing preservation rates are higher. Conclusion It is possible to use the NNT equation alongside projected facial nerve outcomes to estimate benchmarks of minimally acceptable hearing preservation rates.

摘要

目的 本研究的目的是确定前庭神经鞘瘤听力保留手术成功的最低基准,即单个患者听力得以保留的可能性至少与单个患者出现面神经不良结果的可能性相同。设计 这是一项对已发表文献的统计分析。地点 学术性三级医疗中心。主要观察指标 根据已发表的自然史数据,采用需治疗人数(NNT)公式计算不同听力分类方案下可接受的最低听力保留率。结果 鉴于面神经良好结果率分别为85%、90%和95%,在4.7年时,单个患者保留A类和B类听力(美国耳鼻咽喉头颈外科学会分类)且导致面神经不良结果的相应听力保留率分别为70%、65%和60%。如果手术仅局限于内听道肿瘤,这些比率分别降至62%、57%和52%。如果使用单词识别评分分类,所需的听力保留率更高。结论 可以将NNT公式与预计的面神经结果一起用于估计可接受的最低听力保留率基准。

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Hearing preservation after intracanalicular vestibular schwannoma radiosurgery.内听道内前庭神经鞘瘤放射外科手术后的听力保留
Neurosurgery. 2008 Dec;63(6):1054-62; discussion 1062-3. doi: 10.1227/01.NEU.0000335783.70079.85.

本文引用的文献

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Vestibular schwannoma: role of conservative management.前庭神经鞘瘤:保守治疗的作用
J Laryngol Otol. 2010 Mar;124(3):251-7. doi: 10.1017/S0022215109992362. Epub 2009 Dec 11.
6
Long-term hearing preservation in vestibular schwannoma.前庭神经鞘瘤的长期听力保护。
Otol Neurotol. 2010 Feb;31(2):271-5. doi: 10.1097/MAO.0b013e3181c34bda.
8
Hearing preservation after intracanalicular vestibular schwannoma radiosurgery.内听道内前庭神经鞘瘤放射外科手术后的听力保留
Neurosurgery. 2008 Dec;63(6):1054-62; discussion 1062-3. doi: 10.1227/01.NEU.0000335783.70079.85.

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