Mahale Ajit, K V N Dhananjaya, Pai Muralidhar, Poornima Vinaya, Sahu Kausalya Kumari
Professor, Department of Radiodiagnosis, KMC Attavar , Mangalore, Karnataka-575001, India .
J Clin Diagn Res. 2013 Jun;7(6):1197-200. doi: 10.7860/JCDR/2013/2725.3021. Epub 2013 Jun 1.
Giant cell tumours of the clivus are rare. These tumours present in the second and third decades of life and they are slightly more frequent in women than in men. We are presenting a case of a 20 years young patient who came with the complaints of headache, retro-orbital pain and recurrent transient bleeding from the nose since two and half months. MRI of the brain with contrast was done and its features were suggestive of a Giant cell tumour of the clivus. A transnasal endoscopic biopsy was done under general anaesthesia and the histopathology report suggested that the features were of a giant cell tumour. Excision of the mass was done by Transnasal endoscopy. Post operatively, the patient did not recover from the lateral rectus palsy which was there on the right side. The patient was discharged with an advice of a follow up and radiotherapy. Radiation therapy and chemotherapy may be effective as adjuvant treatments. Even though a recurrence usually occurs within 4 years of the initial treatment, these patients will need to be carefully followed for the remainder of their lives.
斜坡巨细胞瘤较为罕见。这些肿瘤多在人生的第二个和第三个十年出现,女性发病略多于男性。我们现报告一例20岁年轻患者,该患者自两个半月以来一直主诉头痛、眶后疼痛及反复短暂鼻出血。进行了增强脑部磁共振成像(MRI)检查,其特征提示为斜坡巨细胞瘤。在全身麻醉下进行了经鼻内镜活检,组织病理学报告显示特征符合巨细胞瘤。通过经鼻内镜切除肿块。术后,患者右侧已存在的外直肌麻痹未恢复。患者出院时被告知要进行随访及放疗。放射治疗和化疗作为辅助治疗可能有效。尽管复发通常发生在初始治疗后的4年内,但这些患者在余生都需要仔细随访。